Evidence map›Paper›PMID 29163355›Full record

ArticleFrontiers in endocrinology2017

Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent.

Bradly M Bauman, Weiling Yin, Andrea C Gore, T John Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Phoenixin-A Pleiotropic Gut-Brain Peptide.International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Bradly M BaumanDepartment of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.
Weiling YinDivision of Pharmacology and Toxicology, Department of Psychology, Institute for Neuroscience, The University of Texas at Austin, Austin, TX, United States.
Andrea C GoreDivision of Pharmacology and Toxicology, Department of Psychology, Institute for Neuroscience, The University of Texas at Austin, Austin, TX, United States.
T John WuDepartment of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.
The University of Texas at Austin · USUniformed Services University of the Health Sciences · US

Funding

The Nonhuman Primate CoreP01AG016765 · NIA · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI BAXTER, MARK G · 1999 to 2016
$26.1M
The GnRH Metabolite, GnRH-(1-5), Functions via an orphan receptor, GPR173R03HD078645 · NICHD · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI WU, T JOHN · 2014 to 2015
$154k
NIA NIH HHS P01 AG016765NICHD NIH HHS R03 HD078645
6 · The paper itself

Abstract

Gonadotropin-releasing hormone (GnRH) is a key regulatory molecule of the hypothalamus-pituitary (PIT)-gonadal (HPG) axis that ultimately leads to the downstream release of estradiol (E

Indexed as

agingEP24.15estradiolgonadotropin-releasing hormonegonadotropin-releasing hormone (1–5)GPR101GPR173

Identifiers

PMID29163355
PMCPMC5663685
OpenAlexW2766578096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.