Evidence map›Paper›PMID 29163229›Full record

ArticleFrontiers in physiology2017

Cx43 Isoform GJA1-20k Promotes Microtubule Dependent Mitochondrial Transport.

Ying Fu, Shan-Shan Zhang, Shaohua Xiao, Wassim A Basheer, Rachel Baum, Irina Epifantseva, TingTing Hong, Robin M Shaw

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Building the bridges: molecular mechanisms of tunneling nanotube formation.Cellular and molecular life sciences : CMLS · 2026
    Review
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  5. Deceiving the gatekeepers: virus modulation of gap junctions.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Connexins and Glucose Metabolism in Cancer.International journal of molecular sciences · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ying FuCedars-Sinai Medical Center, Cedars-Sinai Heart Institute, Los Angeles, CA, United States.
Shan-Shan ZhangCedars-Sinai Medical Center, Cedars-Sinai Heart Institute, Los Angeles, CA, United States.
Shaohua XiaoCedars-Sinai Medical Center, Cedars-Sinai Heart Institute, Los Angeles, CA, United States.
Wassim A BasheerCedars-Sinai Medical Center, Cedars-Sinai Heart Institute, Los Angeles, CA, United States.
Rachel BaumCedars-Sinai Medical Center, Cedars-Sinai Heart Institute, Los Angeles, CA, United States.
Irina EpifantsevaCedars-Sinai Medical Center, Cedars-Sinai Heart Institute, Los Angeles, CA, United States.
TingTing HongCedars-Sinai Medical Center, Cedars-Sinai Heart Institute, Los Angeles, CA, United States.
Robin M ShawCedars-Sinai Medical Center, Cedars-Sinai Heart Institute, Los Angeles, CA, United States.
Cedars-Sinai Medical Center · US

Funding

Training in Advanced Heart Disease ResearchT32HL116273 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI Joshua I Goldhaber, EDUARDO MARBAN · 2013 to 2026
$5.6M
Novel Mechanisms of Cardiac Ion Channel RegulationR01HL094414 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SHAW, ROBIN M · 2009 to 2018
$3.6M
Regulation of Ion Channels at BIN1-induced T-tubule MicrodomainsR01HL133286 · NHLBI · UNIVERSITY OF UTAH · PI HONG, TINGTING · 2016 to 2020
$2.2M
A New Non-Canonical Role for an Alternatively Translated Ion Channel ProteinR01HL138577 · NHLBI · UNIVERSITY OF UTAH · PI SHAW, ROBIN M · 2017 to 2020
$2.1M
NHLBI NIH HHS R01 HL094414NHLBI NIH HHS R01 HL133286NHLBI NIH HHS R01 HL138577NHLBI NIH HHS T32 HL116273
6 · The paper itself

Abstract

Connexin 43 (Cx43, encoded by

Indexed as

alternative translationCx43gap junction proteinmicrotubulemitochondriaoxidative stress

Identifiers

PMID29163229
PMCPMC5682029
OpenAlexW2767344017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.