Evidence map›Paper›PMID 29163180›Full record

ArticleFrontiers in pharmacology2017

Risk Factors of Hypersensitivity to Carboplatin in Patients with Gynecologic Malignancies.

Yu-Hsiao Tai, Yi-Jou Tai, Heng-Cheng Hsu, Shu-Ping Lee, Yun-Yuan Chen, Ying-Cheng Chiang, Yu-Li Chen, Chi-An Chen, Wen-Fang Cheng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yu-Hsiao TaiDepartment of Obstetrics and Gynecology, National Cheng Kung University Hospital, Tainan, Taiwan.
Yi-Jou TaiDepartment of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Heng-Cheng HsuDepartment of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Shu-Ping LeeDepartment of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Yun-Yuan ChenDepartment of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Ying-Cheng ChiangDepartment of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Yu-Li ChenDepartment of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Chi-An ChenDepartment of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Wen-Fang ChengDepartment of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan.
National Taiwan University · TWNational Cheng Kung University Hospital · TWTaiwan Public Television Service Foundation · TWNational Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated the prevalence of and risk factors for hypersensitivity reactions related to carboplatin, which is commonly used to treat gynecological malignancies. All women with pathologically documented ovarian, fallopian tube, or primary peritoneal cancer treated with carboplatin alone or a carboplatin-based combination chemotherapy regimen at a single hospital between January 2006 and December 2013 were retrospectively recruited. We analyzed the incidence, characteristics, risk factors, management, and outcomes of carboplatin-related hypersensitivity reactions among these patients. Among 735 eligible women, 75 (10.2%) experienced a total of 215 carboplatin-related hypersensitivity reaction events. The annual incidence of carboplatin-related hypersensitivity reactions gradually increased from 0.88% in 2006 to 5.42% in 2013. The incidence of carboplatin-related hypersensitivity was higher in patients with advanced stage disease (

Indexed as

carboplatinchemotherapyhypersensitivityovarian cancerrisk factor

Identifiers

PMID29163180
PMCPMC5681487
OpenAlexW2766652053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.