ArticleFrontiers in aging neuroscience2017
Simultaneous Imaging of Cerebrovascular Structure and Function in Hypertensive Rats Using Synchrotron Radiation Angiography.
Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 12 citations in OpenAlex.
- Aniracetam Ameliorates Attention Deficit Hyperactivity Disorder Behavior in Adolescent Mice.eNeuro · 2025Article
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- An updated review on animal models to study attention-deficit hyperactivity disorder.Translational psychiatry · 2024Review
- Real-time X-ray imaging of mouse cerebral microvessels in vivo using a pixel temporal averaging method.Journal of synchrotron radiation · 2022Article
- Sensitive imaging of intact microvesselsIUCrJ · 2020Article
- Dynamic Detection of Thrombolysis in Embolic Stroke Rats by Synchrotron Radiation Angiography.Translational stroke research · 2019Article
- Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats.CNS neuroscience & therapeutics · 2019Article
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9 authors at 3 institutions in 1 country.
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Abstract
Hypertension has a profound influence on the structure and function of blood vessels. Cerebral vessels undergo both structural and functional changes in hypertensive animals. However, dynamic changes of cerebrovasculature and the factors involved in this process are largely unknown. In this study, we explored the dynamic changes of vascular structure in hypertensive rats using novel synchrotron radiation angiography. Twenty-four spontaneously hypertensive rats (SHR) and 24 Sprague-Dawley (SD) rats underwent synchrotron radiation (SR) angiography. Each group had 8 animals. We studied the cerebral vascular changes in SHR over a time period of 3-12-month and performed quantitative analysis. No vascular morphology differences between SHR and SD rats were observed in the early stage of hypertension. The number of twisted blood vessels in the front brain significantly increased at the 9- and 12-month observation time-points in the SHR compared to the SD rats (
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