ArticleFrontiers in human neuroscience2017
A Computational Analysis of Neural Mechanisms Underlying the Maturation of Multisensory Speech Integration in Neurotypical Children and Those on the Autism Spectrum.
Article in Frontiers in human neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- A neuro-computational framework for modeling the development of cross-sensory interactions in Autism: from mechanistic understanding to targeted intervention.Research square · 2026Article
- Space Impacts Temporal Processing via a Visual-Dependent Spatially Organized Neural Architecture.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Disrupted Top-Down Modulation as a Mechanism of Impaired Multisensory Processing in Children with an Autism Spectrum Diagnosis.bioRxiv : the preprint server for biology · 2025Article
- Is Competition the Default Configuration of Cross-Sensory Interactions?The European journal of neuroscience · 2025Article
- Multisensory integration in the mammalian brain: diversity and flexibility in health and disease.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Event-Related Desynchronization of MEG Alpha-Band Oscillations during Simultaneous Presentation of Audio and Visual Stimuli in Children with Autism Spectrum Disorder.Brain sciences · 2023Article
- The Contribution of Visual and Auditory Working Memory and Non-Verbal IQ to Motor Multisensory Processing in Elementary School Children.Brain sciences · 2023Article
- Crossmodal interactions in human learning and memory.Frontiers in human neuroscience · 2023Review
- Atypical development of causal inference in autism inferred through a neurocomputational model.Frontiers in computational neuroscience · 2023Article
- Article
- Resolution of impaired multisensory processing in autism and the cost of switching sensory modality.Communications biology · 2022Article
- Weak observer-level correlation and strong stimulus-level correlation between the McGurk effect and audiovisual speech-in-noise: A causal inference explanation.Cortex; a journal devoted to the study of the nervous system and behavior · 2020Article
- Approaches to Understanding Multisensory Dysfunction in Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2020Review
- Multisensory Audiovisual Processing in Children With a Sensory Processing Disorder (II): Speech Integration Under Noisy Environmental Conditions.Frontiers in integrative neuroscience · 2020Article
- Ripe for solution: Delayed development of multisensory processing in autism and its remediation.Neuroscience and biobehavioral reviews · 2018Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Failure to appropriately develop multisensory integration (MSI) of audiovisual speech may affect a child's ability to attain optimal communication. Studies have shown protracted development of MSI into late-childhood and identified deficits in MSI in children with an autism spectrum disorder (ASD). Currently, the neural basis of acquisition of this ability is not well understood. Here, we developed a computational model informed by neurophysiology to analyze possible mechanisms underlying MSI maturation, and its delayed development in ASD. The model posits that strengthening of feedforward and cross-sensory connections, responsible for the alignment of auditory and visual speech sound representations in posterior superior temporal gyrus/sulcus, can explain behavioral data on the acquisition of MSI. This was simulated by a training phase during which the network was exposed to unisensory and multisensory stimuli, and projections were crafted by Hebbian rules of potentiation and depression. In its mature architecture, the network also reproduced the well-known multisensory McGurk speech effect. Deficits in audiovisual speech perception in ASD were well accounted for by fewer multisensory exposures, compatible with a lack of attention, but not by reduced synaptic connectivity or synaptic plasticity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.