ArticleFrontiers in cellular neuroscience2017
Synchronicity and Rhythmicity of Purkinje Cell Firing during Generalized Spike-and-Wave Discharges in a Natural Mouse Model of Absence Epilepsy.
Article in Frontiers in cellular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 33 citations in OpenAlex.
- miR-9-5p is Downregulated in Serum Extracellular Vesicles of Patients Treated with Biperiden After Traumatic Brain Injury.Molecular neurobiology · 2024Trial
- Quantifying cerebellar signal detectability in MEG and EEG in epilepsy using anatomically informed source modeling.NeuroImage · 2026Article
- Article
- Quantifying Cerebellar Signal Detectability in MEG and EEG in Epilepsy Using Anatomically Informed Source Modeling.bioRxiv : the preprint server for biology · 2026Article
- Early and widespread cerebellar engagement during hippocampal seizures and interictal discharges.Neurobiology of disease · 2025Article
- Climbing fibers selectively recruit disinhibitory interneurons to enhance dendritic calcium signaling in cerebellar Purkinje cells.bioRxiv : the preprint server for biology · 2025Article
- Absence seizures: Update on signaling mechanisms and networks.Epilepsia open · 2025Article
- How and where Effectively Apply Cerebellum Stimulation: The frequency-dependent Modulation of Cerebellar Output by Transcranial Alternating Current Stimulation.Cerebellum (London, England) · 2025Article
- Molecular Mechanisms Underlying the Generation of Absence Seizures: Identification of Potential Targets for Therapeutic Intervention.International journal of molecular sciences · 2024Review
- Patterns of subregional cerebellar atrophy across epilepsy syndromes: An ENIGMA-Epilepsy study.Epilepsia · 2024Article
- The bidirectional relationship between the cerebellum and seizure networks: a double-edged sword.Current opinion in behavioral sciences · 2023Article
- Patterns of subregional cerebellar atrophy across epilepsy syndromes: An ENIGMA-Epilepsy study.bioRxiv : the preprint server for biology · 2023Article
- The cerebellum contributes to generalized seizures by altering activity in the ventral posteromedial nucleus.Communications biology · 2023Article
- The little brain and the seahorse: Cerebellar-hippocampal interactions.Frontiers in systems neuroscience · 2023Review
- Article
- Hyperperfusion in the cerebellum lobule VIIb in patients with epileptic seizures.BMC neurology · 2022Article
- Disruption of Cerebellar-Cerebral Functional Connectivity in Temporal Lobe Epilepsy and the Connection to Language and Cognitive Functions.Frontiers in neuroscience · 2022Article
- The cerebellum and epilepsy.Epilepsy & behavior : E&B · 2021Review
- Gap junction-mediated glycinergic inhibition ensures precise temporal patterning in vocal behavior.eLife · 2021Article
- Alcohol and IL-6 Alter Expression of Synaptic Proteins in Cerebellum of Transgenic Mice with Increased Astrocyte Expression of IL-6.Neuroscience · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Absence epilepsy is characterized by the occurrence of generalized spike and wave discharges (GSWDs) in electrocorticographical (ECoG) recordings representing oscillatory activity in thalamocortical networks. The oscillatory nature of GSWDs has been shown to be reflected in the simple spike activity of cerebellar Purkinje cells and in the activity of their target neurons in the cerebellar nuclei, but it is unclear to what extent complex spike activity is implicated in generalized epilepsy. Purkinje cell complex spike firing is elicited by climbing fiber activation and reflects action potential firing in the inferior olive. Here, we investigated to what extent modulation of complex spike firing is reflected in the temporal patterns of seizures. Extracellular single-unit recordings in awake, head-restrained homozygous
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.