ArticleFrontiers in molecular neuroscience2017
NPAS2 Regulation of Anxiety-Like Behavior and GABAA Receptors.
Article in Frontiers in molecular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 52 citations in OpenAlex.
- Deciphering the circadian signature in acute myeloid leukemia: NPAS2 downregulation as a master predictive feature.Blood research · 2026Article
- Nanoplastics Impair GnRH Neuron Migration and Neuroendocrine Function: Emerging Players in the Pathogenesis of Reproductive Disorders.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- CellWalker2: Multi-omic discovery using hierarchical cell type relationships.Cell genomics · 2025Article
- Sex-specific attenuation of constant light-induced memory impairment and Clock gene expression in brain in hepatic Npas2 knockout mice.Scientific reports · 2025Article
- Beyond vision: effects of light on the circadian clock and mood-related behaviours.Npj biological timing and sleep · 2025Review
- Article
- Using single-sample networks to identify the contrasting patterns of gene interactions and reveal the radiation dose-dependent effects in multiple tissues of spaceflight mice.NPJ microgravity · 2024Article
- The sleep-circadian interface: A window into mental disorders.Proceedings of the National Academy of Sciences of the United States of America · 2024Review
- Adolescent circadian rhythm disruption increases reward and risk-taking.Frontiers in neuroscience · 2024Article
- Machine learning analyses reveal circadian clock features predictive of anxiety among UK biobank participants.Scientific reports · 2023Article
- Differential Expression of Circadian Clock Genes in the Bovine Neuroendocrine Adrenal System.Genes · 2023Article
- Review
- Differential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens Proteome.Journal of proteome research · 2023Article
- Characterization of a loss-of-function NSF attachment protein beta mutation in monozygotic triplets affected with epilepsy and autism using cortical neurons from proband-derived and CRISPR-corrected induced pluripotent stem cell lines.Frontiers in neuroscience · 2023Article
- Emotionally clocked out: cell-type specific regulation of mood and anxiety by the circadian clock system in the brain.Frontiers in molecular neuroscience · 2023Review
- Mood phenotypes in rodent models with circadian disturbances.Neurobiology of sleep and circadian rhythms · 2022Review
- A role for the circadian transcription factor NPAS2 in the progressive loss of non-rapid eye movement sleep and increased arousal during fentanyl withdrawal in male mice.Psychopharmacology · 2022Article
- Astrocyte Molecular Clock Function in the Nucleus Accumbens Is Important for Reward-Related Behavior.Biological psychiatry · 2022Article
- Time of trauma prospectively affects PTSD symptom severity: The impact of circadian rhythms and cortisol.Psychoneuroendocrinology · 2022Article
- Machine learning and expression analyses reveal circadian clock features predictive of anxiety.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
Abnormal circadian rhythms and circadian genes are strongly associated with several psychiatric disorders. Neuronal PAS Domain Protein 2 (NPAS2) is a core component of the molecular clock that acts as a transcription factor and is highly expressed in reward- and stress-related brain regions such as the striatum. However, the mechanism by which NPAS2 is involved in mood-related behaviors is still unclear. We measured anxiety-like behaviors in mice with a global null mutation in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.