Evidence map›Paper›PMID 29163034›Full record

ArticleFrontiers in molecular neuroscience2017

Direct Reprogramming Rather than iPSC-Based Reprogramming Maintains Aging Hallmarks in Human Motor Neurons.

Yu Tang, Meng-Lu Liu, Tong Zang, Chun-Li Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 164 citations in OpenAlex.

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47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Yu TangDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Meng-Lu LiuDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Tong ZangDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Chun-Li ZhangDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, United States.
The University of Texas Southwestern Medical Center · US

Funding

Reprogramming reactive glial cells into functional new neurons after SCIR01NS111776 · NINDS · INDIANA UNIVERSITY INDIANAPOLIS · PI WU, WEI, ZHANG, CHUN-LI · 2020 to 2024
$2.4M
Induced Adult Neurogenesis for Parkinson's DiseaseR01NS092616 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI ZHANG, CHUN-LI · 2016 to 2020
$2.4M
Neurogenesis de novo in the adult central nervous systemDP2OD006484 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI ZHANG, CHUN-LI · 2009 to 2009
$2.4M
Chemical Reprogramming of Traumatic Brain InjuryR01NS099073 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI ZHANG, CHUN-LI · 2017 to 2021
$1.8M
In Vivo Reprogramming of Glial Fate for Spinal Cord RepairR01NS088095 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI ZHANG, CHUN-LI · 2014 to 2018
$1.7M
Reprogramming the Human Glioma GenomeR21NS093502 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI ZHANG, CHUN-LI · 2015 to 2016
$445k
NIH HHS DP2 OD006484NINDS NIH HHS R01 NS088095NINDS NIH HHS R01 NS092616NINDS NIH HHS R01 NS099073NINDS NIH HHS R01 NS111776NINDS NIH HHS R21 NS093502
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

agingALSdirect reprogramminghuman iPSCmotor neuronneural progenitor cellsrejuvenation

Identifiers

PMID29163034
PMCPMC5676779
OpenAlexW2765408167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.