ReviewFrontiers in neuroscience2017
Serotonin Coordinates Responses to Social Stress-What We Can Learn from Fish.
Review in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 116 citations in OpenAlex.
- Genetic Diversity and Runs of Homozygosity in Three Masu Salmon (Biomolecules · 2026Article
- Integrating behaviour, physiology, and immune response to social stress in fish.Frontiers in endocrinology · 2026Review
- Regional brain serotonergic activity as an indicator of chronic stress and compromised welfare in fish.Frontiers in endocrinology · 2026Article
- Physiologically mediated responses in gilthead sea bream (Frontiers in physiology · 2026Article
- Psychobiotics in Aquaculture: Harnessing the Microbiome-Gut-Brain Axis for Stress Management and Production Enhancement in Fish.Animals : an open access journal from MDPI · 2025Review
- Early-life environmental enrichment promotes positive animal welfare for juvenile Atlantic salmon (Salmo salar) in aquaculture research.Scientific reports · 2025Article
- Acute Stress Effects over Time on the Gene Expression and Neurotransmitter Patterns in the Carp (Animals : an open access journal from MDPI · 2024Article
- Individual differences in the boldness of female zebrafish are associated with alterations in serotonin function.The Journal of experimental biology · 2024Article
- Article
- Chronic exposure to tris (2-chloroethyl) phosphate (TCEP) induces brain structural and functional changes in zebrafish (Danio rerio): A comparative study on the environmental and LC50 concentrations of TCEP.Environmental science and pollution research international · 2024Article
- Individual differences in the boldness of female zebrafish are associated with alterations in serotonin function.bioRxiv : the preprint server for biology · 2024Article
- Chronic social isolation affects feeding behavior of juvenile zebrafish (Danio rerio).PloS one · 2024Article
- Effects of Artificial Light at Night on Fitness-Related Traits of Sea Urchin (Animals : an open access journal from MDPI · 2023Article
- Identifying knowledge gaps in understanding the effects of selective serotonin reuptake inhibitors (SSRIs) on fish behaviour.Chemosphere · 2023Review
- Unraveling the serotonin saga: from discovery to weight regulation and beyond - a comprehensive scientific review.Cell & bioscience · 2023Review
- Neuroendocrine mechanisms contributing to the coevolution of sociality and communication.Frontiers in neuroendocrinology · 2023Review
- Effects of different acute stressors on the regulation of appetite genes in the carp (Royal Society open science · 2023Article
- Social stress-induced serotonin dysfunction activates spexin in male Nile tilapia (Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Boldness, activity, and aggression: Insights from a large-scale study in Baltic salmon (Salmo salar L).PloS one · 2023Article
- Unraveling the periprandial changes in brain serotonergic activity and its correlation with food intake-related neuropeptides in rainbow troutFrontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Social interaction is stressful and subordinate individuals are often subjected to chronic stress, which greatly affects both their behavior and physiology. In teleost fish the social position of an individual may have long-term effects, such as effects on migration, age of sexual maturation or even sex. The brain serotonergic system plays a key role in coordinating autonomic, behavioral and neuroendocrine stress responses. Social subordination results in a chronic activation of the brain serotonergic system an effect, which seems to be central in the subordinate phenotype. However, behavioral effects of short-term acute activation of the serotonergic system are less obvious. As in other vertebrates, divergent stress coping styles, often referred to as proactive and reactive, has been described in teleosts. As demonstrated by selective breeding, stress coping styles appear to be partly heritable. However, teleost fish are characterized by plasticity, stress coping style being affected by social experience. Again, the brain serotonergic system appears to play an important role. Studies comparing brain gene expression of fish of different social rank and/or displaying divergent stress coping styles have identified several novel factors that seem important for controlling aggressive behavior and stress coping, e.g., histamine and hypocretin/orexin. These may also interact with brain monoaminergic systems, including serotonin.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.