Evidence map›Paper›PMID 29163000›Full record

ArticleFrontiers in neuroscience2017

Convergence of Cortical, Thalamocortical, and Callosal Pathways during Human Fetal Development Revealed by Diffusion MRI Tractography.

Rongpin Wang, Molly Wilkinson, Tara Kane, Emi Takahashi

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rongpin WangDivision of Newborn Medicine, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Molly WilkinsonDepartment of Behavioral Neuroscience, Northeastern University, Boston, MA, United States.
Tara KaneDepartment of Behavioral Neuroscience, Northeastern University, Boston, MA, United States.
Emi TakahashiDivision of Newborn Medicine, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.

Funding

ULTRAHIGH FIELD TECHNOLOGY FOR FUNCTIONAL IMAGINGP41RR014075 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 1999 to 2011
$16.4M
Development and Organization of the Human Frontal CortexU01MH081896 · NIMH · YALE UNIVERSITY · PI SESTAN, NENAD · 2009 to 2013
$5.7M
A Storage Area Network for Structural and Functional Image AnalysisS10RR023401 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE · 2009 to 2009
$2.0M
Development of Brain Connectivity in Human Fetus, Newborn, and Toddler AgesR01HD078561 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI TAKAHASHI (OKI), EMI · 2014 to 2018
$1.7M
SILICON GRAPHICS PRISM EXTREME 128P/1TBS10RR023043 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI SORENSEN, ALMA GREGORY · 2006 to 2006
$1.5M
Computeserver Structural &Functional Image AnalysisS10RR019307 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE · 2004 to 2004
$496k
Development of Brain Connectivity in the Human FetusR21HD069001 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI TAKAHASHI (OKI), EMI · 2012 to 2013
$467k
Assessment of white matter connectivity in Alexander diseaseR03NS101372 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI TAKAHASHI (OKI), EMI · 2018 to 2019
$177k
Aberrant Patterns of Human Brain Connectivity and Gyral StructuresR03NS091587 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI TAKAHASHI (OKI), EMI · 2015 to 2016
$177k
NCRR NIH HHS P41 RR014075NCRR NIH HHS S10 RR019307NCRR NIH HHS S10 RR023043NCRR NIH HHS S10 RR023401NICHD NIH HHS R01 HD078561NICHD NIH HHS R21 HD069001NIMH NIH HHS U01 MH081896NINDS NIH HHS R03 NS091587NINDS NIH HHS R03 NS101372
6 · The paper itself

Abstract

There has been evidence that during brain development, emerging thalamocortical (TC) and corticothalamic (CT) pathways converge in some brain regions and follow each other's trajectories to their final destinations. Corpus callosal (CC) pathways also emerge at a similar developmental stage, and are known to converge with TC pathways in specific cortical regions in mature brains. Given the functional relationships between TC and CC pathways, anatomical convergence of the two pathways are likely important for their functional integration. However, it is unknown (1) where TC and CT subcortically converge in the human brain, and (2) where TC and CC converge in the cortex of the human brain, due to the limitations of non-invasive methods. The goals of this study were to describe the spatio-temporal relationships in the development of the TC/CT and CC pathways in the human brain, using high-angular resolution diffusion MR imaging (HARDI) tractography. Emerging cortical, TC and CC pathways were identified in

Indexed as

corpus callosalcorticothalamicdevelopmentfetushumanthalamocorticaltractography

Identifiers

PMID29163000
PMCPMC5671991

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.