Evidence map›Paper›PMID 29162978›Full record

ArticleJournal of experimental neuroscience2017

Exploring the Interaction of

Kayly M Lembke, David B Morton

Open access · goldAbstract read
In one paragraph

Article in Journal of experimental neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kayly M LembkeDepartment of Physiology & Pharmacology, Oregon Health & Science University, Portland, OR, USA.
David B MortonDepartment of Integrative Biosciences, Oregon Health & Science University, Portland, OR, USA.
Oregon Health & Science University · US

Funding

Using Drosophila as a model to understand TDP-43 function in ALSR21NS071186 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI MORTON, DAVID B · 2011 to 2012
$410k
NINDS NIH HHS R21 NS071186
6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is the most common adult onset motor neurodegenerative disease. The cause of the disease remains obscure, and as such there is no effective treatment or cure. Amyotrophic lateral sclerosis and other neurodegenerative diseases are frequently characterized by dysfunction of the RNA-binding protein, TDP-43. Using model systems to understand the mechanisms underlying TDP-43 dysfunction should accelerate identification of therapeutic targets. A recent report has shown that motor defects caused by the deletion of the

Indexed as

ALSamyotrophic lateral sclerosisDrosophila melanogasterneurodegenerationvoltage-gated ion channel

Identifiers

PMID29162978
PMCPMC5692131
OpenAlexW2770007452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.