Evidence map›Paper›PMID 29162974›Full record

ArticleCancer informatics2017

Nonmonotonic Pathway Gene Expression Analysis Reveals Oncogenic Role of p27/Kip1 at Intermediate Dose.

Hien H Nguyen, Susan C Tilton, Christopher J Kemp, Mingzhou Song

Open access · goldAbstract read
In one paragraph

Article in Cancer informatics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hien H NguyenDepartment of Computer Science, New Mexico State University, Las Cruces, NM, USA.
Susan C TiltonHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Christopher J KempHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Mingzhou SongDepartment of Computer Science, New Mexico State University, Las Cruces, NM, USA.
Fred Hutch Cancer Center · USNew Mexico State University · US

Funding

NM-INBRE Sequencing and Bioinformatics CoreP20GM103451 · NIGMS · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI Charlotte C. Gard · 2012 to 2026
$61.2M
Tracking and EvaluationU54GM104944 · NIGMS · UNIVERSITY OF NEVADA LAS VEGAS · PI ZHU, YILIANG · 2013 to 2023
$39.6M
Research Education About Cancer and Health (REACH) CoreU54CA132381 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI KAREN R PETERSON · 2007 to 2026
$25.3M
Undergraduate Student Training in Cancer ResearchU54CA132383 · NCI · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI MICHELE Irene SHUSTER · 2007 to 2026
$21.4M
Personalized cancer models to discover and develop new therapeutic targets.U01CA217883 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI KEMP, CHRISTOPHER J · 2017 to 2021
$4.3M
An integrated computational and functional genomics discovery engine for precliniU01CA176303 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI KEMP, CHRISTOPHER J · 2013 to 2016
$4.1M
NCI NIH HHS U01 CA176303NCI NIH HHS U01 CA217883NCI NIH HHS U54 CA132381NCI NIH HHS U54 CA132383NIGMS NIH HHS P20 GM103451NIGMS NIH HHS U54 GM104944
6 · The paper itself

Abstract

The mechanistic basis by which the level of p27

Indexed as

functional pathway analysisnonmonotonic patternsp27tumorigenesis

Identifiers

PMID29162974
PMCPMC5692148
OpenAlexW2768639419

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.