Evidence map›Paper›PMID 29162968›Full record

ArticleBioinformation2017

Cholera host response gene networks: preliminary studies.

Paul Shapshak, Charurut Somboonwit, Shu Cao, John T Sinnott

Abstract read
In one paragraph

Article in Bioinformation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paul ShapshakDivision of Infectious Diseases and International Medicine, Department of Internal Medicine, Morsani College of Medicine, Tampa, FL 33606 USA.
Charurut SomboonwitDivision of Infectious Diseases and International Medicine, Department of Internal Medicine, Morsani College of Medicine, Tampa, FL 33606 USA.
Shu CaoDivision of Infectious Diseases and International Medicine, Department of Internal Medicine, Morsani College of Medicine, Tampa, FL 33606 USA.
John T SinnottDivision of Infectious Diseases and International Medicine, Department of Internal Medicine, Morsani College of Medicine, Tampa, FL 33606 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene network analysis was performed based on published literature describing genes that are possibly interconnected with cholera vaccine responses in vitro in cell culture and in vivo in human patient punch biopsies as well as DNA extracted from blood. These studies produced divergent results. The differences should be replicated and studied further. Included in such studies, patient ethnicities, states of stress, nutrition, and health, as well as the precise characteristics of the various cholera vaccines and modes of delivery need to be considered as well.

Indexed as

Choleragene networksin vitroin vivovaccines

Identifiers

PMID29162968
PMCPMC5680717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.