ArticleScientific reports2017
Ultrasonographic measurement of the optic nerve sheath diameter and its association with eyeball transverse diameter in 585 healthy volunteers.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03691025 (Ultrasonographic Measurement of the Optic Nerve Sheath Diameter and Its Association With Eyeball Transverse Diameter in Robot-assisted Laparoscopic Radical Prostatectomy), which is not on this map. Cited by 45 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ultrasonographic Measurement of the Optic Nerve Sheath Diameter and Its Association With Eyeball Transverse Diameter in Robot-assisted Laparoscopic Radical Prostatectomy
Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic Role of Optic Nerve Sheath Diameter for Neurological Outcomes in Post-Cardiac Arrest Patients: A Systematic Review and Meta-Analysis.BioMed research international · 2020Pooled it
- Association Between Local Anesthetic Volume-Dose Combinations and Optic Nerve Sheath Diameter as an Indirect Marker of Intracranial Pressure During Ultrasound-Guided Supraclavicular Brachial Plexus Block: A Randomized Trial.Medicina (Kaunas, Lithuania) · 2026Trial
- Effect of different anesthesia strategies on intracranial pressure during extubation after intracranial aneurysm embolization: a randomized controlled trial.Scientific reports · 2026Trial
- Trial
- Predictive value of optic nerve sheath diameters on cerebral performance category scale in patients with impaired consciousness in the emergency department: a prospective pilot study.International journal of emergency medicine · 2026Article
- Observational
- Personalized treatment approaches in neurocritical care.Acute and critical care · 2026Article
- Association between perioperative optic nerve sheath diameter and postoperative delirium after Bentall surgery: a prospective observational study.Frontiers in medicine · 2026Article
- Research on the use of bedside ultrasound to quickly evaluate neurological prognosis in patients with ROSC.PloS one · 2026Article
- Advancements in Non-Invasive Intracranial Pressure Monitoring via Optic Nerve Sheath Diameter Measurement.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- Optic nerve sheath diameter measurement in healthy South Iranian adults from a cross-sectional ultrasonographic study.Scientific reports · 2025Article
- Super-resolution multi-contrast unbiased eye atlases with deep probabilistic refinement.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- Article
- Prediction of Intracranial Pressure in Patients with an Aneurysmal Subarachnoid Hemorrhage Using Optic Nerve Sheath Diameter via Explainable Predictive Modeling.Journal of clinical medicine · 2024Article
- Optic nerve sheath diameter/eyeball transverse diameter ratio by ultrasound in prediction of increased intracranial pressure in children with viral encephalitis.Frontiers in pediatrics · 2024Article
- Association between optic nerve sheath diameter/eyeball transverse diameter ratio and neurological outcomes in patients with aneurysmal subarachnoid hemorrhage.Journal of Korean Neurosurgical Society · 2023Article
- Optic Nerve Sheath Diameter: A Cross-Sectional Study of Ultrasonographic Measurement in Healthy Black South African Adults.Life (Basel, Switzerland) · 2023Article
- Extracorporeal Circulation and Optic Nerve Ultrasound: A Pilot Study.Medicina (Kaunas, Lithuania) · 2023Article
- Ultrasound measurement of optic nerve sheath diameter in a healthy adult Colombian population.BMC neurology · 2023Article
- The Association Between Hyponatremia and Optic Nerve Sheath Diameter: A Prospective Study.Cureus · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The optic nerve sheath diameter (ONSD) is considered as an indirect marker for intracranial pressure (ICP). However, the optimal cut-off value for an abnormal ONSD indicating elevated ICP and its associated factors have been unclear. Thus, we investigated normative values for the ONSD using ultrasonography and investigate the potential factors affecting it. We prospectively recruited healthy volunteers between September 2016 and March 2017. A total of 585 individuals were included, in which the mean ONSD was 4.11 mm [95% confidence interval (CI), 4.09-4.14 mm]. Although ONSD was correlated with sex (p = 0.015), height (p = 0.003), and eyeball transverse diameter (ETD) (p < 0.001) in simple linear regression analyses, multiple linear regression analysis revealed that only ETD was independently associated with ONSD (p < 0.001). Accordingly, we further established a normative value for the ONSD/ETD ratio and its associated factors. The mean ONSD/ETD ratio was 0.18 (95% CI, 0.18-0.18), but the ONSD/ETD ratio was not correlated with sex, height, weight, body mass index, and head circumference. Our findings suggest that the ONSD had a strong correlation with ETD, and ONSD/ETD ratio might provide more reliable data than ONSD itself as a marker of ICP.
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