Evidence map›Paper›PMID 29162904›Full record

ArticleScientific reports2017

Whole Y-chromosome sequences reveal an extremely recent origin of the most common North African paternal lineage E-M183 (M81).

Neus Solé-Morata, Carla García-Fernández, Vadim Urasin, Asmahan Bekada, Karima Fadhlaoui-Zid, Pierre Zalloua, David Comas, Francesc Calafell

Abstract read
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Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  10. Phylogeographic review of Y chromosome haplogroups in Europe.International journal of legal medicine · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Neus Solé-MorataInstitute of Evolutionary Biology (CSIC-UPF), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain.ORCID 0000-0003-0433-0843
Carla García-FernándezInstitute of Evolutionary Biology (CSIC-UPF), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain.
Vadim UrasinYFull-Research Group, Moscow, Russia.
Asmahan BekadaDépartement de Biotechnologie, Faculté des Sciences de la Nature et de la Vie, Université Oran 1 (Ahmad Ben Bella), Oran, Algeria.
Karima Fadhlaoui-ZidLaboratoire de Génetique, Immunologie et Pathologies Humaines, Faculté des Sciences de Tunis, Campus Universitaire El Manar II, Université El Manar, Tunis, Tunisia.
Pierre ZallouaThe Lebanese American University, Chouran, Beirut, Lebanon.
David ComasInstitute of Evolutionary Biology (CSIC-UPF), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain. david.comas@upf.edu.
Francesc CalafellInstitute of Evolutionary Biology (CSIC-UPF), Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain. francesc.calafell@upf.edu.ORCID 0000-0002-1083-9438

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

E-M183 (E-M81) is the most frequent paternal lineage in North Africa and thus it must be considered to explore past historical and demographical processes. Here, by using whole Y chromosome sequences from 32 North African individuals, we have identified five new branches within E-M183. The validation of these variants in more than 200 North African samples, from which we also have information of 13 Y-STRs, has revealed a strong resemblance among E-M183 Y-STR haplotypes that pointed to a rapid expansion of this haplogroup. Moreover, for the first time, by using both SNP and STR data, we have provided updated estimates of the times-to-the-most-recent-common-ancestor (TMRCA) for E-M183, which evidenced an extremely recent origin of this haplogroup (2,000-3,000 ya). Our results also showed a lack of population structure within the E-M183 branch, which could be explained by the recent and rapid expansion of this haplogroup. In spite of a reduction in STR heterozygosity towards the West, which would point to an origin in the Near East, ancient DNA evidence together with our TMRCA estimates point to a local origin of E-M183 in NW Africa.

Indexed as

PhylogenyAfrica, NorthernBase SequenceBayes TheoremBlack PeopleChromosomes, Human, YHaplotypesHumansMaleMicrosatellite RepeatsPolymorphism, Single NucleotidePrincipal Component AnalysisTime Factors

Identifiers

PMID29162904
PMCPMC5698413

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.