Evidence map›Paper›PMID 29162896›Full record

ArticleScientific reports2017

β-adrenergic stimulation augments transmural dispersion of repolarization via modulation of delayed rectifier currents I

C Kang, A Badiceanu, J A Brennan, C Gloschat, Y Qiao, N A Trayanova, I R Efimov

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. The Thyroid-cardiac Axis: Thyroid Function, Cardiac Rhythmology, and Sudden Cardiac Death.Endocrine, metabolic & immune disorders drug targets · 2024
    Review
  7. Article
  8. Article
  9. Suppression of amiodarone-induced torsade de pointes by landiolol in a patient with atrial fibrillation-mediated cardiomyopathy.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2021
    Article
  10. Review
  11. Article
  12. Insights into Cardiac IKs (KCNQ1/KCNE1) Channels Regulation.International journal of molecular sciences · 2020
    Review
  13. Neurohormonal Regulation of IJournal of the American Heart Association · 2020
    Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

C KangThe George Washington University, Washington, DC, USA.
A BadiceanuJohn Hopkins University, Baltimore, MD, USA.
J A BrennanThe George Washington University, Washington, DC, USA.
C GloschatThe George Washington University, Washington, DC, USA.
Y QiaoThe George Washington University, Washington, DC, USA.
N A TrayanovaJohn Hopkins University, Baltimore, MD, USA.
I R EfimovThe George Washington University, Washington, DC, USA. efimov@gwu.edu.ORCID 0000-0002-1483-5039
George Washington University · USJohns Hopkins University · US

Funding

Virtual Electrophysiology LaboratoryDP1HL123271 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI TRAYANOVA, NATALIA A. · 2013 to 2017
$4.0M
Exploration of Arrhythmogenic Triggers and Substrates in Heart FailureR01HL126802 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI EFIMOV, IGOR R, GORELIK, JULIA · 2016 to 2019
$2.8M
ARRHYTHMOGENIC REMODELING IN HUMAN HEART FAILURER01HL114395 · NHLBI · WASHINGTON UNIVERSITY · PI EFIMOV, IGOR R · 2012 to 2015
$2.1M
NHLBI NIH HHS DP1 HL123271NHLBI NIH HHS R01 HL114395NHLBI NIH HHS R01 HL126802
6 · The paper itself

Abstract

Long QT syndrome (LQTS) is an inherited or drug induced condition associated with delayed repolarization and sudden cardiac death. The cardiac potassium channel, I

Indexed as

Action PotentialsAdultAgedFemaleHeart Conduction SystemHeart VentriclesHumansMaleMiddle AgedPotassium Channel BlockersPotassium ChannelsReceptors, Adrenergic, betaYoung AdultPotassium Channel BlockersPotassium ChannelsReceptors, Adrenergic, beta

Identifiers

PMID29162896
PMCPMC5698468
OpenAlexW2769580795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.