Evidence map›Paper›PMID 29162875›Full record

Trial reportScientific reports2017

Effect of aerobic exercise and diet on liver fat in pre-diabetic patients with non-alcoholic-fatty-liver-disease: A randomized controlled trial.

Sulin Cheng, Jun Ge, Can Zhao, Shenglong Le, Yifan Yang, Dandan Ke, Na Wu, Xiao Tan, Xiaobo Zhang, Xiaming Du and 7 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 15 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 15 syntheses or guidelines pooled it, 119 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 4 countries.

Sulin ChengExercise, Health and Technology Centre, Department of Physical Education, Shanghai Jiao Tong University, 200240, Shanghai, China. Sulin.cheng@jyu.fi.ORCID 0000-0001-9601-4834
Jun GeShanghai Yangpu district Shidong Hospital, 200090, Shanghai, China.
Can ZhaoSchool of Kinesiology, Shanghai University of Sport, 200438, Shanghai, China.
Shenglong LeExercise, Health and Technology Centre, Department of Physical Education, Shanghai Jiao Tong University, 200240, Shanghai, China.
Yifan YangExercise, Health and Technology Centre, Department of Physical Education, Shanghai Jiao Tong University, 200240, Shanghai, China.
Dandan KeSchool of Kinesiology, Shanghai University of Sport, 200438, Shanghai, China.
Na WuExercise, Health and Technology Centre, Department of Physical Education, Shanghai Jiao Tong University, 200240, Shanghai, China.
Xiao TanExercise, Health and Technology Centre, Department of Physical Education, Shanghai Jiao Tong University, 200240, Shanghai, China.
Xiaobo ZhangExercise, Health and Technology Centre, Department of Physical Education, Shanghai Jiao Tong University, 200240, Shanghai, China.
Xiaming DuShanghai Yangpu district Shidong Hospital, 200090, Shanghai, China.
Jianqin SunClinical Nutrition Centre, Fudan University Huadong Hospital, 200040, Shanghai, China.
Renwei WangSchool of Kinesiology, Shanghai University of Sport, 200438, Shanghai, China.
Yongyong ShiBio-X, Shanghai Jiao Tong University, 200030, Shanghai, China.ORCID 0000-0003-1710-1505
Ronald J H BorraDepartment of Diagnostic Radiology, University of Turku and Turku University Hospital, Turku, Finland.ORCID 0000-0001-8072-1243
Riitta ParkkolaDepartment of Diagnostic Radiology, University of Turku and Turku University Hospital, Turku, Finland.
Petri WiklundFaculty of Sport and Health Sciences, University of Jyväskylä, 40014, Jyväskylä, Finland.
Dajiang LuSchool of Kinesiology, Shanghai University of Sport, 200438, Shanghai, China. ludajiang2000@aliyun.com.
Shanghai Jiao Tong University · CNShanghai University of Sport · CNYangpu Hospital of Tongji University · CNFudan University · CNImperial College London · GBUniversity Medical Center Groningen · NLUniversity of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study aimed to assess whether aerobic exercise (AEx) training and a fibre-enriched diet can reduce hepatic fat content (HFC) and increase glycaemic control in pre-diabetic patients with non-alcoholic fatty liver disease (NAFLD). Six-hundred-and-three patients from seven clinics in Yangpu district, Shanghai, China were recruited. Of them 115 individuals aged 50-65-year fulfilled the inclusion criteria (NAFLD with impaired fasting glucose or impaired glucose tolerance) and were randomly assigned into exercise (AEx n = 29), diet (Diet n = 28), exercise plus diet (AED n = 29), or no-intervention (NI n = 29) groups. Progressive supervised AEx training (60-75% VO2max intensity) was given 2-3 times/week in 30-60 min/sessions, and the diet intervention was provided as lunch with 38% carbohydrate and diet fibre of 12 g/day for 8.6-month. HFC was assessed by

Indexed as

AdiposityDietBiomarkersDisease ProgressionExerciseFemaleGlycated HemoglobinHumansInsulin ResistanceIntention to Treat AnalysisLiverMaleMiddle AgedNon-alcoholic Fatty Liver DiseasePrediabetic StateTreatment OutcomeBiomarkersGlycated Hemoglobin

Identifiers

PMID29162875
PMCPMC5698376
OpenAlexW2769013162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.