Evidence map›Paper›PMID 29162867›Full record

ArticleScientific reports2017

Broad-spectrum antiviral agents: secreted phospholipase A

Ming Chen, Chie Aoki-Utsubo, Masanori Kameoka, Lin Deng, Yutaka Terada, Wataru Kamitani, Kei Sato, Yoshio Koyanagi, Makoto Hijikata, Keiko Shindo and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. New Phenolic Lipids from the Leaves ofMolecules (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Article
  12. Antiviral Effect ofPharmaceuticals (Basel, Switzerland) · 2022
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Antiviral Effects of Animal Toxins: Is There a Way to Drugs?International journal of molecular sciences · 2022
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Ming ChenDepartment of Vaccine and Drug Development, Graduate School of Health Sciences, Kobe University, Kobe, 650-0047, Japan.
Chie Aoki-UtsuboDepartment of International Health, Graduate School of Health Sciences, Kobe University, Kobe, 654-0147, Japan.
Masanori KameokaDepartment of International Health, Graduate School of Health Sciences, Kobe University, Kobe, 654-0147, Japan.ORCID 0000-0001-5525-9915
Lin DengDivision of Infectious Disease Control, Graduate School of Medicine, Kobe University, Kobe, 650-0017, Japan.
Yutaka TeradaLaboratory of Clinical Research on Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, 565-0871, Japan.
Wataru KamitaniLaboratory of Clinical Research on Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, 565-0871, Japan.
Kei SatoLaboratory of Systems Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, 606-8507, Japan.ORCID 0000-0003-4431-1380
Yoshio KoyanagiLaboratory of Systems Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, 606-8507, Japan.
Makoto HijikataLaboratory of Tumour Viruses, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, 606-8507, Japan.
Keiko ShindoLaboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, 606-8507, Japan.
Takeshi NodaLaboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, 606-8507, Japan.
Michinori KoharaInfectious Disease Regulation Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, 156-8506, Japan.
Hak HottaDepartment of Vaccine and Drug Development, Graduate School of Health Sciences, Kobe University, Kobe, 650-0047, Japan. hotta@kobe-u.ac.jp.
Kyoto University · JPKobe University · JPKobe International University · JPThe University of Osaka · JPTokyo Metropolitan Institute of Medical Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV), dengue virus (DENV) and Japanese encephalitis virus (JEV) belong to the family Flaviviridae. Their viral particles have the envelope composed of viral proteins and a lipid bilayer acquired from budding through the endoplasmic reticulum (ER). The phospholipid content of the ER membrane differs from that of the plasma membrane (PM). The phospholipase A

Indexed as

AnimalsAntiviral AgentsCattleCell DeathCell MembraneEndoplasmic ReticulumHemolysisHumansIntracellular MembranesIsoenzymesLipid BilayersMembrane LipidsPhospholipases A2, SecretorySwineTerpenesVirusesAntiviral AgentsIsoenzymesLipid BilayersmanoalideMembrane LipidsPhospholipases A2, SecretoryTerpenesviral envelope lipids

Identifiers

PMID29162867
PMCPMC5698466
OpenAlexW2770379612

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.