ArticleScientific reports2017
Numerical Simulation of Hemodynamic Changes in Central Veins after Tunneled Cuffed Central Venous Catheter Placement in Patients under Hemodialysis.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Central venous catheter tip position and risk of mechanical complications: a systematic review and meta-analysis.Journal of anesthesia · 2026Review
- Development and internal validation of a clinical prediction model for venous thromboembolism in patients with renal insufficiency.Scientific reports · 2026Article
- Fluid Dynamic and in Vitro Blood Study to Understand Catheter-Related Thrombosis.Cardiovascular engineering and technology · 2025Article
- NiagaraFrontiers in bioengineering and biotechnology · 2025Article
- Numerical Study on the Impact of Central Venous Catheter Placement on Blood Flow in the Cavo-Atrial Junction.Annals of biomedical engineering · 2024Article
- Factors Affecting Outcomes of Percutaneous Transluminal Angioplasty for Central Vein Occlusive Disease in the University of the Philippines-Philippine General Hospital: A 10-Year Experience.Acta medica Philippina · 2024Article
- Computational investigation of the haemodynamics shows criticalities of central venous lines used for chronic haemodialysis in children.Frontiers in pediatrics · 2022Article
- Survival Analysis of Tunneled Cuffed Central Venous Catheters in Maintenance Hemodialysis Patients: A Retrospective Study in China.International journal of clinical practice · 2022Article
- Human blood plasma factors affect the adhesion kinetics of Staphylococcus aureus to central venous catheters.Scientific reports · 2020Article
- [Construction of finite element model of left atrial diverticulum based on computed tomography and reverse engineering softwares].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2018Article
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7 authors.
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Abstract
The tunneled central venous catheter (CVC) plays an important role for hemodialysis patients, but CVC-related thrombosis in the central veins remain problematic. This study is the first try to numerically find out what hemodynamic parameters are predisposed to the initiation and formation of thrombus after CVC insertion. And the potential relationship between hemodynamic parameters and the incidence rates of thrombosis occurrence was explored. The results revealed that the CVC insertion led to a significant increase of hydraulic resistance, wide-ranging abnormally high wall shear stress (WSS), and a great loss of flow rotation in the vein. Moreover, the clinical data showed that thrombosis mainly occurred at sections where most blood flow lost spiral rotation after the CVC insertion, but no corresponding match was observed between the occurrence of thrombosis and the flow velocity or WSS. We speculate that the destruction of the flow rotation in the central vein is a precursor to the thrombus formation around CVC, and an introduction of spiral flow with the CVC insertion may possibly help to protect the central vein from thrombosis. Further animal and clinical experiments should be carried out to test and verify this speculation.
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