Evidence map›Paper›PMID 29162829›Full record

ArticleNature communications2017

Single-molecule visualization of conformational changes and substrate transport in the vitamin B

Joris M H Goudsmits, Dirk Jan Slotboom, Antoine M van Oijen

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The Evolution of ABC Importers.Journal of molecular biology · 2025
    Review
  5. Article
  6. Article
  7. microRNA maintains nutrient homeostasis in the symbiont-host interaction.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Linking function to global and local dynamics in an elevator-type transporter.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Single-molecule FRET methods to study the dynamics of proteins at work.Current opinion in biomedical engineering · 2019
    Article
  17. Article
  18. Article
  19. Noncanonical role for the binding protein in substrate uptake by the MetNI methionine ATP Binding Cassette (ABC) transporter.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Joris M H GoudsmitsZernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.
Dirk Jan SlotboomZernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands. d.j.slotboom@rug.nl.ORCID http://orcid.org/0000-0002-5804-9689
Antoine M van OijenZernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands. vanoijen@uow.edu.au.ORCID http://orcid.org/0000-0002-1794-5161
University of Groningen · NL

Funding

European Research Council 282083
6 · The paper itself

Abstract

ATP-binding cassette (ABC) transporters form the largest class of active membrane transport proteins. Binding and hydrolysis of ATP by their highly conserved nucleotide-binding domains drive conformational changes of the complex that mediate transport of substrate across the membrane. The vitamin B

Indexed as

Adenosine TriphosphateATP-Binding Cassette TransportersEscherichia coliEscherichia coli ProteinsModels, MolecularPeriplasmic Binding ProteinsProtein ConformationVitamin B 12Adenosine TriphosphateATP-Binding Cassette TransportersBtuC peptide, E coliBtuD peptide, E colibtuF protein, E coliEscherichia coli ProteinsPeriplasmic Binding ProteinsVitamin B 12

Identifiers

PMID29162829
PMCPMC5698293
OpenAlexW2769232299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.