Evidence map›Paper›PMID 29162710›Full record

ArticlemBio2017

UDP-4-Keto-6-Deoxyglucose, a Transient Antifungal Metabolite, Weakens the Fungal Cell Wall Partly by Inhibition of UDP-Galactopyranose Mutase.

Liang Ma, Omar Salas, Kyle Bowler, Maor Bar-Peled, Amir Sharon

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Inhibitory Mechanisms ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Liang MaDepartment of Molecular Biology and Ecology of Plants, Tel Aviv University, Tel Aviv, Israel.
Omar SalasComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
Kyle BowlerComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
Maor Bar-PeledComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA peled@ccrc.uga.edu amirsh@ex.tau.ac.il.
Amir SharonDepartment of Molecular Biology and Ecology of Plants, Tel Aviv University, Tel Aviv, Israel peled@ccrc.uga.edu amirsh@ex.tau.ac.il.
University of Georgia · USTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Can accumulation of a normally transient metabolite affect fungal biology? UDP-4-keto-6-deoxyglucose (UDP-KDG) represents an intermediate stage in conversion of UDP-glucose to UDP-rhamnose. Normally, UDP-KDG is not detected in living cells, because it is quickly converted to UDP-rhamnose by the enzyme UDP-4-keto-6-deoxyglucose-3,5-epimerase/-4-reductase (ER). We previously found that deletion of the

Indexed as

Antifungal AgentsBotrytisCell WallCrystallography, X-RayGlucoseIntramolecular TransferasesKineticsMetabolic Networks and PathwaysPhaseolusPlant LeavesUridine DiphosphateUridine Diphosphate SugarsAntifungal AgentsGlucoseIntramolecular TransferasesUDP-4-keto-6-deoxyglucoseUDP-galactopyranose mutaseUDP-rhamnoseUridine DiphosphateUridine Diphosphate SugarsBotrytis cinereafungal cell wallfungal nucleotide sugar metabolismgalactofuranosemetabolic intermediateUDP-4-keto-6-deoxyglucoseUDP-galactopyranose mutase

Identifiers

PMID29162710
PMCPMC5698552
OpenAlexW2769251313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.