Evidence map›Paper›PMID 29162686›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Atypical activation of dendritic cells by

Anton Götz, Mei San Tang, Maureen C Ty, Charles Arama, Aissata Ongoiba, Didier Doumtabe, Boubacar Traore, Peter D Crompton, P'ng Loke, Ana Rodriguez

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Infection and immunity · 2024
    Article
  5. Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  6. eLife · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Oxidative Stress in Malaria: Potential Benefits of Antioxidant Therapy.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Review
  13. Article
  14. Immunosuppression in Malaria: DoPathogens (Basel, Switzerland) · 2021
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Inotodiol FromFrontiers in immunology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Anton GötzDepartment of Microbiology, New York University School of Medicine, New York, NY 10016; anton.goetz@nih.gov ana.rodriguez@nyumc.org.
Mei San TangDepartment of Microbiology, New York University School of Medicine, New York, NY 10016.
Maureen C TyDepartment of Microbiology, New York University School of Medicine, New York, NY 10016.
Charles AramaMalaria Research and Training Centre, Department of Epidemiology of Parasitic Diseases, International Center of Excellence in Research, University of Sciences, Technique, and Technology of Bamako, 91094 Bamako, Mali.
Aissata OngoibaMalaria Research and Training Centre, Department of Epidemiology of Parasitic Diseases, International Center of Excellence in Research, University of Sciences, Technique, and Technology of Bamako, 91094 Bamako, Mali.
Didier DoumtabeMalaria Research and Training Centre, Department of Epidemiology of Parasitic Diseases, International Center of Excellence in Research, University of Sciences, Technique, and Technology of Bamako, 91094 Bamako, Mali.
Boubacar TraoreMalaria Research and Training Centre, Department of Epidemiology of Parasitic Diseases, International Center of Excellence in Research, University of Sciences, Technique, and Technology of Bamako, 91094 Bamako, Mali.
Peter D CromptonLaboratory of Immunogenetics, Malaria Infection Biology and Immunity Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852.
P'ng LokeDepartment of Microbiology, New York University School of Medicine, New York, NY 10016.
Ana RodriguezDepartment of Microbiology, New York University School of Medicine, New York, NY 10016; anton.goetz@nih.gov ana.rodriguez@nyumc.org.
New York University · USUniversity of Bamako · MLNational Institutes of Health · US

Funding

Project-005UL1TR001445 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BREDELLA, MIRIAM ANTOINETTE, HOCHMAN, JUDITH S · 2015 to 2025
$103.5M
Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 1985 to 2026
$83.1M
Mechanisms of naturally-acquired immunity to malaria and clinical trials of anti-malaria monoclonal antibodiesZIAAI001155 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CROMPTON, PETER · 2011 to 2025
$30.9M
NCATS NIH HHS UL1 TR001445NCI NIH HHS P30 CA016087
6 · The paper itself

Abstract

Dendritic cells (DCs) are activated by pathogens to initiate and shape immune responses. We found that the activation of DCs by

Indexed as

Host-Parasite InteractionsLymphocyte ActivationAntigens, CDCD4-Positive T-LymphocytesChemokine CCL2Chemokine CCL5Chemokine CXCL10Chemokine CXCL9Coculture TechniquesDendritic CellsErythrocytesGene Expression RegulationHLA-DR AntigensHumansInterleukin-10Interleukin-1betaAntigens, CDCCL2 protein, humanCCL5 protein, humanChemokine CCL2Chemokine CCL5Chemokine CXCL10Chemokine CXCL9CXCL10 protein, humanCXCL9 protein, humanHLA-DR AntigensIL10 protein, humanIL1B protein, humanIL6 protein, humanInterleukin-10Interleukin-1betaInterleukin-6LipopolysaccharidesTumor Necrosis Factor-alphaactivationcytokinesdendritic cellsmalariaPlasmodium falciparum

Identifiers

PMID29162686
PMCPMC5724257
OpenAlexW2769499678

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.