Evidence map›Paper›PMID 29162669›Full record

ArticleBioscience reports2018

Non-labeled lensless micro-endoscopic approach for cellular imaging through highly scattering media.

Omer Wagner, Aditya Pandya, Yoav Chemla, Hadar Pinhas, Irina Schelkanova, Asaf Shahmoon, Yossi Mandel, Alexandre Douplik, Zeev Zalevsky

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Omer WagnerFaculty of Engineering and the Nanotechnology Center, Bar Ilan University, Ramat-Gan 5290002, Israel omer.wagner@biu.ac.il.
Aditya PandyaPhysics Department, Ryerson University, Toronto, Canada.
Yoav ChemlaInstitute for Nanotechnology and Advanced Materials (BINA), Bar Ilan University, Ramat Gan, Israel.
Hadar PinhasFaculty of Engineering and the Nanotechnology Center, Bar Ilan University, Ramat-Gan 5290002, Israel.
Irina SchelkanovaPhysics Department, Ryerson University, Toronto, Canada.
Asaf ShahmoonFaculty of Engineering and the Nanotechnology Center, Bar Ilan University, Ramat-Gan 5290002, Israel.
Yossi MandelInstitute for Nanotechnology and Advanced Materials (BINA), Bar Ilan University, Ramat Gan, Israel.
Alexandre DouplikPhysics Department, Ryerson University, Toronto, Canada.
Zeev ZalevskyFaculty of Engineering and the Nanotechnology Center, Bar Ilan University, Ramat-Gan 5290002, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe an imaging approach based on an optical setup made up of a miniature, lensless, minimally invasive endoscope scanning a sample and matching post processing techniques that enable enhanced imaging capabilities. The two main scopes of this article are that this approach enables imaging beyond highly scattering medium and increases the resolution and signal to noise levels reaching single cell imaging. Our approach has more advantages over ordinary endoscope setups and other imaging techniques. It is not mechanically limited by a lens, the stable but flexible fiber can acquire images over long time periods (unlike current imaging methods such as OCT etc.), and the imaging can be obtained at a certain working distance above the surface, without interference to the imaged object. Fast overlapping scans enlarge the region of interest, enhance signal to noise levels and can also accommodate post-processing, super-resolution algorithms. Here we present that due to the setup properties, the overlapping scans also lead to dramatic enhancement of non-scattered signal to scattered noise. This enables imaging through highly scattering medium. We discuss results obtained from

Indexed as

EndoscopesAnimalsDimethylpolysiloxanesHumansImage EnhancementMinimally Invasive Surgical ProceduresRatsRetinabaysilonDimethylpolysiloxanesepithelial cellsFiber optics imagingimaging techniquesImaging through Scattering mediaretinaSuperresolution

Identifiers

PMID29162669
PMCPMC5784180

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.