Evidence map›Paper›PMID 29162625›Full record

ArticleGenetics2018

Sgs1 Binding to Rad51 Stimulates Homology-Directed DNA Repair in

Lillian Campos-Doerfler, Salahuddin Syed, Kristina H Schmidt

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lillian Campos-DoerflerDepartment of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, Florida 33620.
Salahuddin SyedDepartment of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, Florida 33620.
Kristina H SchmidtDepartment of Cell Biology, Microbiology and Molecular Biology, University of South Florida, Tampa, Florida 33620 kschmidt@usf.edu.
University of South Florida · USMoffitt Cancer Center · US

Funding

Suppression of translocations by RecQ-like DNA helicasesR01GM081425 · NIGMS · UNIVERSITY OF SOUTH FLORIDA · PI SCHMIDT, KRISTINA · 2008 to 2018
$2.6M
Cholinergic regulation of NF-kB in sepsisR01GM084125 · NIGMS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI ULLOA, LUIS · 2008 to 2012
$1.5M
NIGMS NIH HHS R01 GM081425NIGMS NIH HHS R01 GM084125
6 · The paper itself

Abstract

Accurate repair of DNA breaks is essential to maintain genome integrity and cellular fitness. Sgs1, the sole member of the RecQ family of DNA helicases in

Indexed as

Recombinational DNA RepairDNA DamageEnzyme ActivationExodeoxyribonucleasesGenomic InstabilityHomologous RecombinationMutationPhenotypeProtein BindingProtein Interaction Domains and MotifsRad51 RecombinaseRecQ HelicasesSaccharomyces cerevisiaeSaccharomyces cerevisiae Proteinsexodeoxyribonuclease IExodeoxyribonucleasesRad51 RecombinaseRecQ HelicasesSaccharomyces cerevisiae ProteinsSGS1 protein, S cerevisiaeDNA damageDNA repairhomologous recombinationRad51Sgs1

Identifiers

PMID29162625
PMCPMC5753853
OpenAlexW2769876921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.