Evidence map›Paper›PMID 29162623›Full record

ArticleBiology open2017

Elimination of classically-activated macrophages in tumor-conditioned medium by alternatively-activated macrophages.

Fidel-Nicolás Lolo, Cristina Rius, Sergio Casas-Tintó

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Fidel-Nicolás LoloMolecular Oncology Programme, Spanish National Cancer Centre (CNIO), Melchor Fernández Almagro, 3, Madrid 28034, Spain scasas@cajal.csic.es flolo@cnic.es.ORCID http://orcid.org/0000-0003-1635-4770
Cristina RiusLaboratory of Molecular and Genetic Cardiovascular Pathophysiology, Centro Nacional de Investigaciones Cardiovasculares (CNIC) and CIBER de Enfermedades Cardiovasculares, Melchor Fernández Almagro, 3, 28029 Madrid, Spain.
Sergio Casas-TintóMolecular, Cellular and Developmental Neurobiology Department, Cajal Institute (CSIC), Avda. Doctor Arce, 37, Madrid 28002, Spain scasas@cajal.csic.es flolo@cnic.es.ORCID http://orcid.org/0000-0002-9589-9981
Spanish National Centre for Cardiovascular Research · ESInstituto Cajal · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular interactions are critical during development, tissue fitness and epithelial tumor development. The expression levels of specific genes confer to tumoral cells a survival advantage versus the normal neighboring cells. As a consequence, cells surrounding tumors are eliminated and engulfed by macrophages. We propose a novel scenario in which circulating cells facing a tumor can reproduce these cellular interactions.

Indexed as

Alternatively-activated macrophagesApoptosisClassically-activated macrophagesTumoral environment

Identifiers

PMID29162623
PMCPMC5769648
OpenAlexW2773301930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.