Evidence map›Paper›PMID 29162183›Full record

ArticleDevelopment and psychopathology2017

Dimensions of childhood adversity have distinct associations with neural systems underlying executive functioning.

Margaret A Sheridan, Matthew Peverill, Amy S Finn, Katie A McLaughlin

Registry-linked trialAbstract read
In one paragraph

Article in Development and psychopathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06119503 (Peer Delivered Episodic Future Thinking to Improve MOUD Treatment Engagement Among Returning Citizens - A Randomized Controlled Trial), which is not on this map. Cited by 136 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
136citing papers in PubMed, 3 pooled it
20.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06119503 nacompletednot on this mapstarted 2023, after this paper: background citation

Peer Delivered Episodic Future Thinking to Improve MOUD Treatment Engagement Among Returning Citizens - A Randomized Controlled Trial

TypeinterventionalSponsorHenry Ford Health SystemRan2023 to 2025Enrolled40ConditionsBehavior, HealthArmsElongating Time HOrizons for Reentry (ETHoR), Standardized Episodic Thinking (SET)
3 · Its place in the literature

Who cites it

136 citing papers in PubMed, 3 syntheses or guidelines pooled it, 266 citations in OpenAlex.

  1. Dimensions of early life adversity and cardiometabolic health in adulthood: A systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
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  15. Longitudinal neurocognitive trajectories in a large cohort of youth who use cannabis: combining self-report and toxicology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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76 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Margaret A SheridanUniversity of North Carolina,Chapel Hill.
Matthew PeverillUniversity of Toronto.
Amy S FinnUniversity of Washington.
Katie A McLaughlinUniversity of Toronto.
University of Toronto · CAUniversity of North Carolina at Chapel Hill · USUniversity of Washington · US

Funding

Intellectual and Developmental Disabilities Research CenterU54HD083091 · NICHD · UNIVERSITY OF WASHINGTON · PI MARAVILLA, KENNETH R · 2014 to 2019
$7.9M
Child Trauma and the Development of Neural Systems Underlying Emotion RegulationR01MH103291 · NIMH · UNIVERSITY OF WASHINGTON · PI MCLAUGHLIN, KATIE · 2014 to 2018
$3.8M
Deprivation and Threat: Dimensions of Early Experience and Neural DevelopmentR01MH106482 · NIMH · UNIVERSITY OF WASHINGTON · PI MCLAUGHLIN, KATIE · 2016 to 2020
$3.1M
Neural Markers of the Transition from ADHD risk before age 7 to stable diagnosisK01MH092555 · NIMH · BOSTON CHILDREN'S HOSPITAL · PI SHERIDAN, MARGARET ANN · 2010 to 2014
$907k
NICHD NIH HHS U54 HD083091NIMH NIH HHS K01 MH092555NIMH NIH HHS R01 MH103291NIMH NIH HHS R01 MH106482
6 · The paper itself

Abstract

Childhood adversity is associated with increased risk for psychopathology. Neurodevelopmental pathways underlying this risk remain poorly understood. A recent conceptual model posits that childhood adversity can be deconstructed into at least two underlying dimensions, deprivation and threat, that are associated with distinct neurocognitive consequences. This model argues that deprivation (i.e., a lack of cognitive stimulation and learning opportunities) is associated with poor executive function (EF), whereas threat is not. We examine this hypothesis in two studies measuring EF at multiple levels: performance on EF tasks, neural recruitment during EF, and problems with EF in daily life. In Study 1, deprivation (low parental education and child neglect) was associated with greater parent-reported problems with EF in adolescents (N = 169; 13-17 years) after adjustment for levels of threat (community violence and abuse), which were unrelated to EF. In Study 2, low parental education was associated with poor working memory (WM) performance and inefficient neural recruitment in the parietal and prefrontal cortex during high WM load among adolescents (N = 51, 13-20 years) after adjusting for abuse, which was unrelated to WM task performance and neural recruitment during WM. These findings constitute strong preliminary evidence for a novel model of the neurodevelopmental consequences of childhood adversity.

Indexed as

AdolescentBrainChild AbuseExecutive FunctionFemaleHumansMagnetic Resonance ImagingMaleMemory, Short-TermNeuropsychological TestsParentsViolenceYoung Adult

Identifiers

PMID29162183
PMCPMC5733141
OpenAlexW2768125376

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.