Trial reportPublic health nutrition2018
Vitamin D status is associated with underweight and stunting in children aged 6-36 months residing in the Ecuadorian Andes.
Trial report in Public health nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association Between Vitamin D Status and Undernutrition Indices in Children: A Systematic Review and Meta-Analysis of Observational Studies.Frontiers in pediatrics · 2021Pooled it
- Nutritional Stunting Is Linked to Reduced Oral Microbiome Stability and Reconfigured Microbial Networks in Children: A Pilot Intervention Study.Pathogens (Basel, Switzerland) · 2026Trial
- Prenatal nutrition supplementation and growth biomarkers in preadolescent Bangladeshi children: A birth cohort study.Maternal & child nutrition · 2022Trial
- The effect of vitamin D supplementation and nutritional intake on skeletal maturity and bone health in socio-economically deprived children.European journal of nutrition · 2021Trial
- Associations of IGF-1, vitamin D, and bone minerals with short stature in children aged 24-59 months.Frontiers in endocrinology · 2026Article
- The Association of Vitamin D, Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF), and Glial Cell-Derived Neurotrophic Factor (GDNF) with Development in Children.Children (Basel, Switzerland) · 2025Article
- Serum Levels of IL-6, IL-10, TNF-α, and Vitamin D: Their Correlation with Acute Otitis Media in Short-Stature Pediatric Patients.Journal of inflammation research · 2025Article
- Factors Associated with Vitamin A and Vitamin D Profiles among Stunted Children in Bogor, Indonesia.Medical journal of the Islamic Republic of Iran · 2025Article
- Article
- Association Between Vitamin D Levels and Developmental Status in Short-Stature Children.Children (Basel, Switzerland) · 2024Article
- The Association between Vitamin D, Interleukin-4, and Interleukin-10 Levels and CD23+ Expression with Bronchial Asthma in Stunted Children.Biomedicines · 2023Article
- Micronutrients and Nutrition Status of School-Aged Children in Indonesia.Journal of nutrition and metabolism · 2023Article
- Stunting as a Risk Factor for Asthma: The Role of Vitamin D, Leptin, IL-4, and CD23.Medicina (Kaunas, Lithuania) · 2022Review
- Relationships between Body Weight Status and Serum Levels of Adipokine, Myokine and Bone Metabolism Parameters in Healthy Normal Weight and Thin Children.Journal of clinical medicine · 2022Article
- Vitamin D deficiency among apparently healthy children and children with common medical illnesses in Sub-Saharan Africa: A systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2022Review
- Article
- Prevalence and predictors of vitamin D deficiency in young African children.BMC medicine · 2021Article
- Prevalence and Correlates of Vitamin D Deficiency among Young South African Infants: A Birth Cohort Study.Nutrients · 2021Article
- The association of serum levels of zinc and vitamin D with wasting among Iranian pre-school children.Eating and weight disorders : EWD · 2021Article
- The impact of maternal and early life malnutrition on health: a diet-microbe perspective.BMC medicine · 2020Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectiveThere is limited knowledge on vitamin D status of children residing in the Andes and its association with undernutrition. We evaluated the vitamin D status of children residing in a low socio-economic status (SES) setting in the Ecuadorian Andes and assessed the association between vitamin D status, stunting and underweight. We hypothesized that children who were underweight would have lower serum 25-hydroxyvitamin D (25(OH)D) levels and lower 25(OH)D levels would be associated with a higher risk of stunting.
designWe conducted a cross-sectional secondary analysis of a randomized controlled trial, the Vitamin A, Zinc and Pneumonia study. Children had serum 25(OH)D concentrations measured. A sensitivity analysis was undertaken to determine a vitamin D cut-off specific for our endpoints. Associations between serum 25(OH)D and underweight (defined as weight-for-age Z-score≤-1) and stunting (defined as height-for-age Z-score≤-2) were assessed using multivariate logistic regression.
settingChildren residing in five low-SES peri-urban neighbourhoods near Quito, Ecuador. SUBJECTS: Children (n 516) aged 6-36 months.
resultsMean serum 25(OH)D concentration was 58·0 (sd 17·7) nmol/l. Sensitivity analysis revealed an undernutrition-specific 25(OH)D cut-off of <42·5 nmol/l; 18·6 % of children had serum 25(OH)D<42·5 nmol/l. Children who were underweight were more likely to have serum 25(OH)D<42·5 nmol/l (adjusted OR (aOR)=2·0; 95 % CI 1·2, 3·3). Children with low serum 25(OH)D levels were more likely to be stunted (aOR=2·8; 95 % CI 1·6, 4·7).
conclusionsLow serum 25(OH)D levels were more common in underweight and stunted Ecuadorian children.
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