Evidence map›Paper›PMID 29162104›Full record

ArticleBMC veterinary research2017

Elimination kinetics of eugenol in grass carp in a simulated transportation setting.

Dong-Hao Zhao, Chang-Liang Ke, Qi Liu, Xu-Feng Wang, Qiang Wang, Liu-Dong Li

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 4 countries.

Dong-Hao ZhaoKey Laboratory of Aquatic Product Processing, Ministry of Agriculture, Guangzhou, 510300, People's Republic of China.
Chang-Liang KeKey Laboratory of Aquatic Product Processing, Ministry of Agriculture, Guangzhou, 510300, People's Republic of China.
Qi LiuKey Laboratory of Aquatic Product Processing, Ministry of Agriculture, Guangzhou, 510300, People's Republic of China.
Xu-Feng WangKey Laboratory of Aquatic Product Processing, Ministry of Agriculture, Guangzhou, 510300, People's Republic of China.
Qiang WangKey Laboratory of Aquatic Product Processing, Ministry of Agriculture, Guangzhou, 510300, People's Republic of China.
Liu-Dong LiKey Laboratory of Aquatic Product Processing, Ministry of Agriculture, Guangzhou, 510300, People's Republic of China. dhao138@126.com.ORCID http://orcid.org/0000-0002-4672-9986
National Quality Inspection and Testing Center for Surveying and Mapping Products · CNMinistry of Agriculture and Rural Development · PL

Funding

the National Key Project for Agro-product Quality & Safety Risk Assessment, PRC GJFP201501003
6 · The paper itself

Abstract

backgroundFish are vulnerable to stress from over-crowding during transportation and eugenol is the most common sedative used to minimize fish injury. The ADI value of 2.5 mg/kg is recommended by the Joint FAO/WHO Expert Committee on Food Additives. The aim of this work was to study the elimination kinetics of eugenol following exposure of grass carp to a eugenol bath in a simulated transportation setting.

resultsGrass carp, Ctenopharyngodon idella (120 fish) were exposed for 24 h to a 10 mg/L eugenol bath. Sampling was performed during a 96 h period after the 24 h bath. Eight fish were sampled at each time point and muscle, plasma and liver concentrations of the drug were determined by ultra-performance liquid chromatography-tandem mass spectrometry. The concentration-time data of eugenol in each tissue were analyzed using non-compartmental methods. The peak concentrations (C

conclusionsThe drug concentrations in muscle tissue at 8 h were lower than the recommended ADI value.

Indexed as

AnimalsCarpsCrowdingDose-Response Relationship, DrugEugenolHalf-LifeHypnotics and SedativesLiverMuscle, SkeletalTransportationEugenolHypnotics and SedativesAnestheticClove oilCtenopharyngodon idellaDrug eliminationFood safety risk

Identifiers

PMID29162104
PMCPMC5699182
OpenAlexW2770128353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.