Evidence map›Paper›PMID 29162084›Full record

SynthesisBMC musculoskeletal disorders2017

Infection following fractures of the proximal tibia - a systematic review of incidence and outcome.

Ralf Henkelmann, Karl-Heinz Frosch, Richard Glaab, Helmut Lill, Christian Schoepp, Dominik Seybold, Christoph Josten, Pierre Hepp, Committee TRAUMA of the AGA-Society for Arthroscopy and Joint Surgery

Abstract readSystematic Review
In one paragraph

Synthesis in BMC musculoskeletal disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Do superficial infections increase the risk of deep infections in tibial plateau and plafond fractures?European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023
    Trial
  3. Multifunctional TPU-HAp/HA-TiOInternational journal of pharmaceutics: X · 2026
    Article
  4. Article
  5. Biomechanical performance of proximal tibia fracture plates: A review.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Does pes anserinus tenotomy affect surgical site infection rate in operative tibial plateau fractures?European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024
    Article
  13. Article
  14. Article
  15. High-energy open-fracture model with initial experience of fluorescence-guided bone perfusion assessment.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Two-level fixation with headless compression screws for tibial plateau fractures.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ralf HenkelmannDepartment of Orthopedics, Trauma and Plastic Surgery, University of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.
Karl-Heinz FroschDepartment of Trauma and Reconstructive Surgery with Divion of Knee and Shoulder Surgery, Sports Traumatology, Asklepios Clinic St. Georg, Lohmühlenstr. 5, 20099, Hamburg, Germany.
Richard GlaabDepartmet of Traumatology, Cantonal Hospital Aarau, Tellstrasse 25, CH-5001, Aarau, Switzerland.
Helmut LillDepartment of Trauma and Reconstructive Surgery, DIAKOVERE Friederikenstift gGmbH, Humboldtstr. 5, 30169, Hannover, Germany.
Christian SchoeppDepartement of Orthopedic and Trauma Surgery, Berufsgenossenschaftliche Unfallklinik Duisburg, Großenbaumer Allee 250, 47249, Duisburg, Germany.
Dominik SeyboldDepartment of General and Trauma Surgery, University Bergmannsheil Bochum, Ruhr-University Bochum, Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany.
Christoph JostenDepartment of Orthopedics, Trauma and Plastic Surgery, University of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.
Pierre HeppDepartment of Orthopedics, Trauma and Plastic Surgery, University of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany. pierre.hepp@medizin.uni-leipzig.de.
Committee TRAUMA of the AGA-Society for Arthroscopy and Joint Surgery

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo systematically review all available studies of operatively treated proximal tibia fractures and to report the incidence of superficial or deep infection and subsequent outcomes.

methodsA systematic review of the literature in Medline, Cochrane, Embase and GoogleScholar was conducted to identify studies with cohorts of patients with infection after surgical treatment of proximal tibia fractures. Studies were included according to predefined inclusion and exclusion criteria. The studies were analysed for methodological deficiencies and quality of outcome reporting based on the Level of Evidence (LOE) and Coleman Methodology Scoring (CMS.)

resultsIn total 32 studies were included. There was heterogeneity between the studies, in terms of subject of the studies, outcome criteria, fracture type and classification, surgical techniques and length of follow-up. Therefore, no meta-analysis could be performed. The average CMS was 54.2 (range 36-75). The included studies were 25 case series (LOE IV), 6 were prospective cohort studies (LOE III) and one was a prospective randomized trial (LOE I). 203 (12.3%, range: 2.6-45.0%) infections occurred in the overall population (n = 2063). Those were divided into 129 deep infections and 74 superficial infections. Revision due to infection was reported in 29 studies, microbiological results in 6, respectively. 72 (55,8%) of 129 cases reporting outcome after deep infection had an unsatisfactory outcome with substantial limitations of the affected joint and leg.

conclusionsPostoperative infections are a challenge, sometimes requiring several revisions and often with a worse outcome. Further studies with structured study protocols should be performed for a better understanding of risk factors to improve treatment outcomes.

Indexed as

Fracture FixationHumansIncidencePostoperative ComplicationsReoperationRisk FactorsSurgical Wound InfectionTibiaTibial FracturesTreatment OutcomeOutcome after infectionProximal tibia fractureSurgical site infectionTibia plateau fracture

Identifiers

PMID29162084
PMCPMC5699108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.