Observational studyBiological research for nursing2018
An Exploration of the Determinants of Gestational Weight Gain in African American Women: Genetic Factors and Energy Expenditure.
Observational study in Biological research for nursing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Randomized Controlled Trial of Home-Based Lifestyle Therapy on Postpartum Weight in Underserved Women with Overweight or Obesity.Obesity (Silver Spring, Md.) · 2019Trial
- Gestational Weight Gain: Is the Role of Genetic Variants a Determinant? A Review.International journal of molecular sciences · 2024Review
- Association between Gestational Weight Gain and Maternal and Birth Outcomes in Northern Ghana.BioMed research international · 2024Article
- Coping with Stress in Complicated Pregnancy and Gestational Weight Gain.International journal of environmental research and public health · 2021Article
- Biological changes in the pregnancy-postpartum period and subsequent cardiometabolic risk-UPSIDE MOMS: A research protocol.Research in nursing & health · 2021Article
- Resting Energy Expenditure Relationship with Macronutrients and Gestational Weight Gain: A Pilot Study.Nutrients · 2020Article
- Energy Intake Requirements in Pregnancy.Nutrients · 2019Review
- Do we need race-specific resting metabolic rate prediction equations?Nutrition & diabetes · 2019Article
- Propensity for adverse pregnancy outcomes in African-American women may be explained by low energy expenditure in early pregnancy.The American journal of clinical nutrition · 2018Article
- Energy Expenditure in Pregnant Women with Obesity Does Not Support Energy Intake Recommendations.Obesity (Silver Spring, Md.) · 2018Observational
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundExcessive gestational weight gain (GWG) has a long-term impact on women's body weight and contributes to the development of obesity in the mother and her child. Many risk factors for GWG have been identified, but to date, only 6-33.8% of the variance in GWG has been explained. The purpose of this study was to evaluate the overall variance of GWG that can be explained by including weight-adjusted resting metabolic rate (aRMR) and a genetic risk score constructed on obesity-related genes in addition to sociodemographic and lifestyle factors.
methodsIn this observational study involving 55 African American women, data collected/measured during pregnancy included sociodemographic factors, medical information, lifestyle factors, aRMR, and seven obesity-related genes. Multivariable linear regression was performed to evaluate the variance in GWG explained by the potential risk factors listed above.
resultsThe mean GWG was 15 kg (±7.5 kg), and 63.6% of women gained more than the Institute of Medicine's GWG recommendations. The final regression model explained 53.3% of the variance in GWG. Higher genetic risk score, lower aRMR, and higher dietary intake of total energy and percentage of fat were significantly associated with increased GWG ( p < .05). These factors explained 18% additional variance in GWG over that explained by significant sociodemographic and lifestyle factors in the analysis (i.e., maternal age, prepregnancy body mass index, parity, illegal drug use, and education).
conclusionOverall, our results indicate that the genetic risk score, aRMR, and dietary intake have a substantial impact on GWG in African American women.
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