ArticleEnvironment international2018
Ambient air pollution, adipokines, and glucose homeostasis: The Framingham Heart Study.
Article in Environment international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Association between maternal exposure to pollutant particulate matter 2.5 and congenital heart defects: a systematic review.JBI database of systematic reviews and implementation reports · 2019Pooled it
- Associations of Exposure to Air Pollution with Insulin Resistance: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2018Pooled it
- Impact of Parental or First-Degree Family History of Diabetes on Diabetes Incidence and Progression During Long-term Follow-up in the Diabetes Prevention Program Outcomes Study.Diabetes care · 2025 · on this mapTrial
- Impact of the Wood-BurningEnvironmental health perspectives · 2025Trial
- Effects of Outdoor and Household Air Pollution on Hand Grip Strength in a Longitudinal Study of Rural Beijing Adults.International journal of environmental research and public health · 2025Article
- Exposure to air pollution is associated with adipokines in midlife women: The Study of Women's Health Across the Nation.The Science of the total environment · 2024Article
- Review
- A review of air pollution as a driver of cardiovascular disease risk across the diabetes spectrum.Frontiers in endocrinology · 2024Review
- Early-life exposure to residential black carbon and childhood cardiometabolic health.Environmental research · 2023Article
- Long-term effects of air pollutants on respiratory and cardiovascular mortality in a port city along the Adriatic sea.BMC pulmonary medicine · 2023Article
- Association between long-term air pollution exposure and insulin resistance independent of abdominal adiposity in Korean adults.Scientific reports · 2022Article
- Traffic-related air pollution, biomarkers of metabolic dysfunction, oxidative stress, and CC16 in children.Journal of exposure science & environmental epidemiology · 2022Article
- Near-roadway air pollution, immune cells and adipokines among obese young adults.Environmental health : a global access science source · 2022Article
- The Association between Exposure to Residential Indoor Volatile Organic Compounds and Measures of Central Arterial Stiffness in Healthy Middle-Aged Men and Women.International journal of environmental research and public health · 2022Article
- Ozone Exposure, Outdoor Physical Activity, and Incident Type 2 Diabetes in the SALSA Cohort of Older Mexican Americans.Environmental health perspectives · 2021Article
- Traffic-related air pollution is associated with glucose dysregulation, blood pressure, and oxidative stress in children.Environmental research · 2021Article
- Long-term exposure to ambient fine particulate matter and fasting blood glucose level in a Chinese elderly cohort.The Science of the total environment · 2020Article
- Susceptibility Variations in Air Pollution Health Effects: Incorporating Neuroendocrine Activation.Toxicologic pathology · 2019Article
- Lack of association between particulate air pollution and blood glucose levels and diabetic status in peri-urban India.Environment international · 2019Article
- Air Pollution, Oxidative Stress, and Diabetes: a Life Course Epidemiologic Perspective.Current diabetes reports · 2019Review
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 2 countries.
Funding
Abstract
objectiveTo examine associations of proximity to major roadways, sustained exposure to fine particulate matter (PM
methodsWe included 5958 participants from the Framingham Offspring cohort examination cycle 7 (1998-2001) and 8 (2005-2008) and Third Generation cohort examination cycle 1 (2002-2005) and 2 (2008-2011), who did not have type 2 diabetes at the time of examination visit. We calculated 2003 annual average PM
resultsThe mean age was 51years and 55% were women. Participants who lived 64m (25th percentile) from a major roadway had 0.28% (95% CI: 0.05%, 0.51%) higher fasting plasma glucose than participants who lived 413m (75th percentile) away, and the association appeared to be driven by participants who lived within 50m from a major roadway. Higher exposures to 3- to 7-day moving averages of BC and NO
conclusionsLiving closer to a major roadway or acute exposure to traffic-related air pollutants were associated with dysregulated glucose homeostasis but not with adipokines among participants from the Framingham Offspring and Third Generation cohorts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.