Evidence map›Paper›PMID 29161566›Full record

ArticleCurrent biology : CB2017

Endosomal Trafficking: Retromer and Retriever Are Relatives in Recycling.

David C Gershlick, María Lucas

Abstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Biological Basis of Cell Trafficking: A General Overview.Journal of inherited metabolic disease · 2025
    Review
  5. Article
  6. Article
  7. Beneath the surface: endosomal GPCR signaling.Trends in biochemical sciences · 2024
    Review
  8. Review
  9. Article
  10. Novel loss-of-function variant in DENND5A impedes melanosomal cargo transport and predisposes to familial cutaneous melanoma.Genetics in medicine : official journal of the American College of Medical Genetics · 2022
    Article
  11. Review
  12. Deliver on Time or Pay the Fine: Scheduling in Membrane Trafficking.International journal of molecular sciences · 2021
    Review
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

David C GershlickCell Biology and Neurobiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda MD 20892, USA. Electronic address: david.gershlick@nih.gov.
María LucasStructural Biology Unit, CIC bioGUNE, Bizkaia Technology Park, 48160 Derio, Spain. Electronic address: mlucas@cicbiogune.es.

Funding

Medical Research Council MR/K018299/1Medical Research Council MR/P018807/1
6 · The paper itself

Abstract

Transmembrane proteins are sorted from endosomes to avoid lysosomal degradation. A recent study has identified a new multimeric complex called retriever that is essential for recycling numerous cell-surface cargoes from endosomes and is structurally and functionally related to the well-characterised retromer complex.

Indexed as

EndosomesLysosomesCell MembraneMembrane ProteinsProtein TransportMembrane Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.