Editorial: Wnt Signaling Related to Subchondral Bone Density and Cartilage Degradation in Osteoarthritis.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. Dickkopf-3 enhances the chondroprotective effect of chondrogenic progenitor cells in a rat model of posttraumatic osteoarthritis.Journal of orthopaedic surgery and research · 2025
   Article
2. Development of novel osteoarthritis therapy by targeting AMPK-β-catenin-Runx2 signaling.Genes & diseases · 2025
   Review
3. Systemic inhibition or global deletion of CaMKK2 protects against post-traumatic osteoarthritis.Osteoarthritis and cartilage · 2022
   Article
4. Low bone mass resulting from impaired estrogen signaling in bone increases severity of load-induced osteoarthritis in female mice.Bone · 2021
   Article
5. Early inhibition of subchondral bone remodeling slows load-induced posttraumatic osteoarthritis development in mice.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021
   Article
6. Xanthan Gum Ameliorates Osteoarthritis and Mitigates Cartilage Degradation via Regulation of the Wnt3a/β-Catenin Signaling Pathway.Medical science monitor : international medical journal of experimental and clinical research · 2019
   Article
7. Mechanobiological Mechanisms of Load-Induced Osteoarthritis in the Mouse Knee.Journal of biomechanical engineering · 2019
   Article
8. Bone Microdamage in Acute Knee Injury.Current rheumatology reports · 2018
   Review

Corrections and comments

• Comment on
  Loading-Induced Reduction in Sclerostin as a Mechanism of Subchondral Bone Plate Sclerosis in Mouse Knee Joints During Late-Stage Osteoarthritis.2018

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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