ArticleNucleic acids research2018
MethBank 3.0: a database of DNA methylomes across a variety of species.
Article in Nucleic acids research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
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- Toti: An integrated multi-omics database to decipher the epigenetic regulation of gene expression in totipotent stem cells.Stem cell reports · 2025Article
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- Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2024.Nucleic acids research · 2024Article
- Unlocking the secrets: the power of methylation-based cfDNA detection of tissue damage in organ systems.Clinical epigenetics · 2023Review
- Human VDAC pseudogenes: an emerging role for VDAC1P8 pseudogene in acute myeloid leukemia.Biological research · 2023Article
- MethBank 4.0: an updated database of DNA methylation across a variety of species.Nucleic acids research · 2023Article
- Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2023.Nucleic acids research · 2023Article
- Databases and prospects of dynamic gene regulation in eukaryotes: A mini review.Computational and structural biotechnology journal · 2023Review
- Epigenetic modifications: Allusive clues of lncRNA functions in plants.Computational and structural biotechnology journal · 2023Review
- Epigenetic targets in B- and T-cell lymphomas: latest developments.Therapeutic advances in hematology · 2023Review
- Article
- Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2022.Nucleic acids research · 2022Article
- scMethBank: a database for single-cell whole genome DNA methylation maps.Nucleic acids research · 2022Article
- ASMdb: a comprehensive database for allele-specific DNA methylation in diverse organisms.Nucleic acids research · 2022Article
- EWAS Open Platform: integrated data, knowledge and toolkit for epigenome-wide association study.Nucleic acids research · 2022Article
- DiseaseMeth version 3.0: a major expansion and update of the human disease methylation database.Nucleic acids research · 2022Article
- The 2022 Nucleic Acids Research database issue and the online molecular biology database collection.Nucleic acids research · 2022Article
- Genome Warehouse: A Public Repository Housing Genome-scale Data.Genomics, proteomics & bioinformatics · 2021Article
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10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MethBank (http://bigd.big.ac.cn/methbank) is a database that integrates high-quality DNA methylomes across a variety of species and provides an interactive browser for visualization of methylation data. Here, we present an updated implementation of MethBank (version 3.0) by incorporating more DNA methylomes from multiple species and equipping with more enhanced functionalities for data annotation and more friendly web interfaces for data presentation, search and visualization. MethBank 3.0 features large-scale integration of high-quality methylomes, involving 34 consensus reference methylomes derived from a large number of human samples, 336 single-base resolution methylomes from different developmental stages and/or tissues of five plants, and 18 single-base resolution methylomes from gametes and early embryos at multiple stages of two animals. Additionally, it is enhanced by improving the functionalities for data annotation, which accordingly enables systematic identification of methylation sites closely associated with age, sites with constant methylation levels across different ages, differentially methylated promoters, age-specific differentially methylated cytosines/regions, and methylated CpG islands. Moreover, MethBank provides tools to estimate human methylation age online and to identify differentially methylated promoters, respectively. Taken together, MethBank is upgraded with significant improvements and advances over the previous version, which is of great help for deciphering DNA methylation regulatory mechanisms for epigenetic studies.
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