ArticleEuropean heart journal2018
Quantifying infective endocarditis risk in patients with predisposing cardiac conditions.
Article in European heart journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 5 of them syntheses that pooled it.
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Who cites it
57 citing papers in PubMed, 5 syntheses or guidelines pooled it, 188 citations in OpenAlex.
- Pooled it
- Recent infective endocarditis research findings suggest dentists prescribe prophylactic antibiotics for patients having a bicuspid aortic valve or mitral valve prolapse.Medicina oral, patologia oral y cirugia bucal · 2023Pooled it
- Antibiotic prophylaxis before dental procedures to prevent infective endocarditis: a systematic review.Infection · 2023Pooled it
- Comparison of infective endocarditis risk between balloon and self-expandable valves following transcatheter aortic valve replacement: systematic review and meta-analysis.Cardiovascular intervention and therapeutics · 2021Pooled it
- Epidemiology of infective endocarditis beforeTherapeutic advances in cardiovascular diseasePooled it
- Valve-Specific Anatomy and Structural Determinants of Susceptibility to Infective Endocarditis: A Review.Journal of clinical medicine · 2026Review
- Article
- Standardized mortality ratio in adults with congenital heart disease.European heart journal open · 2025Article
- Recurrences of the infective endocarditis: clinical features and outcomes. Results from the Polish infective endocarditis registry (POL-ENDO).International journal of cardiology. Heart & vasculature · 2025Article
- ENDOCOR: a nationwide consortium of endocarditis teams-initiating a registry for infective endocarditis within the Netherlands Heart Registration.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025Article
- Epidemiological, clinical and microbiological aspects of infective endocarditis in Türkiye.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Article
- The ratio of blood urea nitrogen to high-density lipoprotein cholesterol: a novel risk-stratifying tool for infective endocarditis.Lipids in health and disease · 2025Article
- Mapping Review of the Correlations Between Periodontitis, Dental Caries, and Endocarditis.Dentistry journal · 2025Review
- Transthoracic Echocardiography in Assessing Patients with Suspected Infective Endocarditis (TEASE): An Exploratory Study.Journal of clinical medicine · 2025Article
- The emerging challenge ofClinical microbiology reviews · 2024Review
- Review
- Increase in Oral Streptococcal Endocarditis Among Moderate-Risk Patients: Impact of Guideline Changes on Endocarditis Prevention.JACC. Advances · 2024Article
- Value of Time-Resolved Cardiac CT in Children and Young Adults with Congenital Heart Disease and Infective Endocarditis.Pediatric cardiology · 2024Article
- A Case Report of Acute Infective Endocarditis Caused by Aggregatibacter aphrophilus Involving the Tricuspid Valve.Cureus · 2024Article
- An infective endocarditis complicated by multiple septic emboli: case report.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024Article
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Authors and funding
7 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims: There are scant comparative data quantifying the risk of infective endocarditis (IE) and associated mortality in individuals with predisposing cardiac conditions. Methods and results: English hospital admissions for conditions associated with increased IE risk were followed for 5 years to quantify subsequent IE admissions. The 5-year risk of IE or dying during an IE admission was calculated for each condition and compared with the entire English population as a control. Infective endocarditis incidence in the English population was 36.2/million/year. In comparison, patients with a previous history of IE had the highest risk of recurrence or dying during an IE admission [odds ratio (OR) 266 and 215, respectively]. These risks were also high in patients with prosthetic valves (OR 70 and 62) and previous valve repair (OR 77 and 60). Patients with congenital valve anomalies (currently considered 'moderate risk') had similar levels of risk (OR 66 and 57) and risks in other 'moderate-risk' conditions were not much lower. Congenital heart conditions (CHCs) repaired with prosthetic material (currently considered 'high risk' for 6 months following surgery) had lower risk than all 'moderate-risk' conditions-even in the first 6 months. Infective endocarditis risk was also significant in patients with cardiovascular implantable electronic devices. Conclusion: These data confirm the high IE risk of patients with a history of previous IE, valve replacement, or repair. However, IE risk in some 'moderate-risk' patients was similar to that of several 'high-risk' conditions and higher than repaired CHC. Guidelines for the risk stratification of conditions predisposing to IE may require re-evaluation.
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