ReviewAnnals of the American Thoracic Society2017
Pathophysiology to Phenotype in the Asthma of Obesity.
Review in Annals of the American Thoracic Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Is Bariatric Surgery Better than Nonsurgical Weight Loss for Improving Asthma Control? A Systematic Review.Obesity surgery · 2021Pooled it
- The Impact of BMI on the Effect of Biologic Agents for Severe Asthma.Pulmonary therapy · 2026Review
- Exploring the association between asthma and frailty: a cross-sectional and a bidirectional Mendelian randomization study.Archives of medical science : AMS · 2026Article
- Role of body anthropometry in severe asthmatic patients: Evidences from the Severe Asthma Network in Italy (SANI) registry.The World Allergy Organization journal · 2025Article
- Exploring the Asthma - Obesity Link Using Advanced Imaging Techniques.Physiological research · 2025Review
- Corticosteroid insensitivity in obese asthma: potential mechanisms and therapeutic perspectives.Frontiers in allergy · 2025Review
- Factors associated with having uncontrolled asthma in rural Appalachia.The Journal of asthma : official journal of the Association for the Care of Asthma · 2024Article
- The Role of Peptides in Asthma-Obesity Phenotype.International journal of molecular sciences · 2024Review
- The Role of Comorbidities in Difficult-to-Control Asthma in Adults and Children.The journal of allergy and clinical immunology. In practice · 2022Article
- Effect modification by age of the association between obstructive lung diseases, smoking, and COVID-19 severity.BMJ open respiratory research · 2021Article
- Asthma and Three Colinear Comorbidities: Obesity, OSA, and GERD.The journal of allergy and clinical immunology. In practice · 2021Review
- Adiponectin and Asthma: Knowns, Unknowns and Controversies.International journal of molecular sciences · 2021Review
- Dysregulation of Pyruvate Kinase M2 Promotes Inflammation in a Mouse Model of Obese Allergic Asthma.American journal of respiratory cell and molecular biology · 2021Article
- Atopy and pulmonary function among healthy-weight and overweight/obese children with asthma.Pediatric pulmonology · 2021Article
- Obesity Does Not Increase the Risk of Asthma Readmissions.Journal of clinical medicine · 2020Article
- Debugging Obesity-related Airway Hyperresponsiveness by Modulating the Microbiome.American journal of respiratory cell and molecular biology · 2019Article
- Older age and obesity are associated with increased airway closure in response to methacholine in patients with asthma.Respirology (Carlton, Vic.) · 2019Article
- Bariatric surgery: a potential cure for asthma?European respiratory review : an official journal of the European Respiratory Society · 2019Review
- Genetics and Gene-Environment Interactions in Childhood and Adult Onset Asthma.Frontiers in pediatrics · 2019Review
- Having concomitant asthma phenotypes is common and independently relates to poor lung function in NHANES 2007-2012.Clinical and translational allergy · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Obesity affects numerous diseases, including asthma, for reasons that remain incompletely understood. Recent research suggests that the asthma of obesity is not a single disease, and that it breaks out into at least two distinct phenotypes. One phenotype is conventional allergic asthma modulated by obesity, whereas another arises solely due to the presence of obesity. The latter is postulated to be a consequence of the chronic lung compression caused by the obese chest wall in individuals with particularly collapsible lungs. Allergic obese asthma, on the other hand, appears to result from the way that obesity affects the immune system, which we hypothesize can be understood in terms of effects on the dynamic regulation of the inflammatory response.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.