Evidence map›Paper›PMID 29161073›Full record

ArticleAmerican journal of public health2018

Evaluating Public Health Interventions: 7. Let the Subject Matter Choose the Effect Measure: Ratio, Difference, or Something Else Entirely.

Donna Spiegelman, Polyna Khudyakov, Molin Wang, Tyler J Vanderweele

Abstract read
In one paragraph

Article in American journal of public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. The Interaction Continuum.Epidemiology (Cambridge, Mass.) · 2019
    Review
  8. Article
  9. Spiegelman and Zhou Respond.American journal of public health · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Donna SpiegelmanDonna Spiegelman is with the departments of Epidemiology, Biostatistics, Nutrition, and Global Health, Harvard T. H. Chan School of Public Health, Boston, MA. Donna Spiegelman and Molin Wang are also with the Channing Division of Network Medicine, Brigham and Women's Hospital, Boston. Polyna Khudyakov is with the Department of Epidemiology, Harvard T. H. Chan School of Public Health. Molin Wang is with the departments of Epidemiology, Biostatistics, and Medicine, Harvard T. H. Chan School of Public Health. Tyler J. Vanderweele is with the departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health.
Polyna KhudyakovDonna Spiegelman is with the departments of Epidemiology, Biostatistics, Nutrition, and Global Health, Harvard T. H. Chan School of Public Health, Boston, MA. Donna Spiegelman and Molin Wang are also with the Channing Division of Network Medicine, Brigham and Women's Hospital, Boston. Polyna Khudyakov is with the Department of Epidemiology, Harvard T. H. Chan School of Public Health. Molin Wang is with the departments of Epidemiology, Biostatistics, and Medicine, Harvard T. H. Chan School of Public Health. Tyler J. Vanderweele is with the departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health.
Molin WangDonna Spiegelman is with the departments of Epidemiology, Biostatistics, Nutrition, and Global Health, Harvard T. H. Chan School of Public Health, Boston, MA. Donna Spiegelman and Molin Wang are also with the Channing Division of Network Medicine, Brigham and Women's Hospital, Boston. Polyna Khudyakov is with the Department of Epidemiology, Harvard T. H. Chan School of Public Health. Molin Wang is with the departments of Epidemiology, Biostatistics, and Medicine, Harvard T. H. Chan School of Public Health. Tyler J. Vanderweele is with the departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health.
Tyler J VanderweeleDonna Spiegelman is with the departments of Epidemiology, Biostatistics, Nutrition, and Global Health, Harvard T. H. Chan School of Public Health, Boston, MA. Donna Spiegelman and Molin Wang are also with the Channing Division of Network Medicine, Brigham and Women's Hospital, Boston. Polyna Khudyakov is with the Department of Epidemiology, Harvard T. H. Chan School of Public Health. Molin Wang is with the departments of Epidemiology, Biostatistics, and Medicine, Harvard T. H. Chan School of Public Health. Tyler J. Vanderweele is with the departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health.

Funding

Comprehensive Translational Science Analytics Tools for the Global Health AgendaDP1ES025459 · NIEHS · YALE UNIVERSITY · PI SPIEGELMAN, DONNA L · 2014 to 2018
$4.1M
New Methods for the design and evaluation of large HIV prevention interventionsR01AI112339 · NIAID · YALE UNIVERSITY · PI SPIEGELMAN, DONNA L · 2014 to 2017
$2.7M
Theory and methods for interactionR56ES017876 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI TCHETGEN TCHETGEN, ERIC JOEL, VANDERWEELE, TYLER · 2016 to 2016
$150k
NIAID NIH HHS R01 AI112339NIEHS NIH HHS DP1 ES025459NIEHS NIH HHS R56 ES017876
6 · The paper itself

Abstract

We define measures of effect used in public health evaluations, which include the risk difference and the risk ratio, the population-attributable risk, years of life lost or gained, disability-adjusted life years, quality-adjusted life years, and the incremental cost-effectiveness ratio. Except for the risk ratio, all of these are absolute effect measures. For constructing externally generalizable absolute measures of effect when there is superior fit of the multiplicative model, we suggest using the multiplicative model to estimate relative risks, which will often be obtained in simple linear form with no interactions, and then converting these to the desired absolute measure. The externally generalizable absolute measure of effect can be obtained by suitably standardizing to the risk factor distribution of the population to which the results are to be generalized. External generalizability will often be compromised when absolute measures are computed from study populations with risk factor distributions different from those of the population to whom the results are to be generalized, even when these risk factors are not confounders of the intervention effect.

Indexed as

Models, StatisticalResearch DesignCost-Benefit AnalysisHumansOdds RatioPublic HealthQuality-Adjusted Life YearsRisk Factors

Identifiers

PMID29161073
PMCPMC5719681

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.