Evidence map›Paper›PMID 29161012›Full record

ReviewAnalytical chemistry2018

Top-Down Proteomics: Ready for Prime Time?

Bifan Chen, Kyle A Brown, Ziqing Lin, Ying Ge

Erratum issuedAbstract readReview
In one paragraph

Review in Analytical chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 111 papers.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed.

  1. Review
  2. Proteoforms as the true units of physiological function.European journal of applied physiology · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Top-down proteomics.Nature reviews. Methods primers · 2024
    Article
  20. Article

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Bifan ChenDepartment of Chemistry, University of Wisconsin-Madison , Madison, Wisconsin 53706, United States.ORCID 0000-0003-0379-0821
Kyle A BrownDepartment of Chemistry, University of Wisconsin-Madison , Madison, Wisconsin 53706, United States.
Ziqing LinDepartment of Cell and Regenerative Biology, University of Wisconsin-Madison , Madison, Wisconsin 53705, United States.ORCID 0000-0003-0464-5263
Ying GeDepartment of Chemistry, University of Wisconsin-Madison , Madison, Wisconsin 53706, United States.ORCID 0000-0001-5211-6812

Funding

Deciphering Myofilament Modifications in Ischemic CardiomyopathyR01HL109810 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI GE, YING · 2013 to 2024
$3.5M
Top Down Proteomics Of Myofilaments In Heart FailureR01HL096971 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI GE, YING · 2011 to 2021
$3.3M
Enabling Top-Down Proteomics through Materials Chemistry and NanotechnologyR01GM117058 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI GE, YING, JIN, SONG · 2015 to 2023
$2.7M
Ultra High Resolution Mass Spectrometer for Biomedical ResearchS10OD018475 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI GE, YING · 2015 to 2015
$2.0M
NHLBI NIH HHS R01 HL096971NHLBI NIH HHS R01 HL109810NIGMS NIH HHS R01 GM117058NIH HHS S10 OD018475
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HumansProteomics

Identifiers

PMID29161012
PMCPMC6138622

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.