ArticleCancer2018
Social integration and survival after diagnosis of colorectal cancer.
Article in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 88 citations in OpenAlex.
- A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality.Nature human behaviour · 2023Pooled it
- Social isolation as a risk factor for all-cause mortality: Systematic review and meta-analysis of cohort studies.PloS one · 2023Pooled it
- Social determinants of colorectal cancer risk, stage, and survival: a systematic review.International journal of colorectal disease · 2020Pooled it
- Uncovering Relationships Between Demoralization, Attachment, and Social Support in Oncology Patients.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026Observational
- The importance of social vulnerability and exclusion in cancer prognosis and survival: a scoping review.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Review
- The association between residential natural vegetation exposure at diagnosis and colorectal cancer-specific mortality among colorectal cancer cases in Kentucky.Environmental research · 2026Article
- The mediating roles of intimate relationships and constructive communication in the association between self-disclosure and benefit finding among patients with colorectal cancer.Asia-Pacific journal of oncology nursing · 2025Article
- Narrative and cognitive behavioral therapy improve psychosocial and oncologic outcomes after abdominoperineal resection: a randomized controlled trial.Journal of cancer survivorship : research and practice · 2025Article
- The association of cancer-related fatigue on the social, vocational and healthcare-related dimensions of cancer survivorship.Journal of cancer survivorship : research and practice · 2025Article
- Network of job demands-resources and depressive symptoms in critical care nurses: a nationwide cross-sectional study.Critical care (London, England) · 2025Article
- Article
- Social supports in patients with cancer attending an Irish cancer center: a cross-sectional study.The oncologist · 2024Article
- Social Determinants of Health and the Link to Colorectal Cancer Outcomes.Current treatment options in oncology · 2024Review
- Association between social background and implementation of postoperative adjuvant chemotherapy for older patients undergoing curative resection of colorectal cancers, sub-analysis of the HiSCO-04 study.International journal of colorectal disease · 2023Article
- Survival of Middle Eastern and North African Individuals Diagnosed with Colorectal Cancer: A Population-Based Study in California.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023Article
- Addressing Social Determinants of Health to Reduce Disparities Among Individuals with Cancer: Insights for Rehabilitation Professionals.Current oncology reports · 2023Review
- Sex and gender perspectives in colorectal cancer.ESMO open · 2023Review
- Exposome approach for identifying modifiable factors for the prevention of colorectal cancer.Scientific reports · 2022Article
- Establishment and validation of a postoperative predictive model for patients with colorectal mucinous adenocarcinoma.World journal of surgical oncology · 2022Article
- Lack of a caregiver is associated with shorter survival in myeloma patients undergoing autologous stem cell transplantation.Leukemia & lymphoma · 2022Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundAlthough larger social networks have been associated with lower all-cause mortality, few studies have examined whether social integration predicts survival outcomes among patients with colorectal cancer (CRC). The authors examined the association between social ties and survival after CRC diagnosis in a prospective cohort study.
methodsParticipants included 896 women in the Nurses' Health Study who were diagnosed with stage I, II, or III CRC between 1992 and 2012. Stage was assigned using the American Joint Committee on Cancer criteria. Social integration was assessed every 4 years since 1992 using the Berkman-Syme Social Network Index, which included marital status, social network size, contact frequency, religious participation, and other social group participation.
resultsDuring follow-up, there were 380 total deaths, 167 of which were due to CRC. In multivariable analyses, women who were socially integrated before diagnosis had a subsequent reduced risk of all-cause mortality (hazard ratio [HR], 0.65; 95% confidence interval [95% CI], 0.46-0.92) and CRC mortality (HR, 0.63; 95% CI, 0.38-1.06) compared with women who were socially isolated. In particular, women with more intimate ties (family and friends) had lower all-cause mortality (HR, 0.61; 95% CI, 0.42-0.88) and CRC mortality (HR, 0.59; 95% CI, 0.34-1.03) compared with those with few intimate ties. Participation in religious or community activities was not found to be related to outcomes. The analysis of postdiagnosis social integration yielded similar results.
conclusionsSocially integrated women were found to have better survival after a diagnosis of CRC, possibly due to beneficial caregiving from their family and friends. Interventions aimed at strengthening social network structures to ensure access to care may be valuable programmatic tools in the management of patients with CRC. Cancer 2018;124:833-40. © 2017 American Cancer Society.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.