Evidence map›Paper›PMID 29160791›Full record

ArticleMolecules (Basel, Switzerland)2017

Antimalarial Activity of Acetylenic Thiophenes from Echinops hoehnelii Schweinf.

Helen Bitew, Wendimagegn Mammo, Ariaya Hymete, Mariamawit Yonathan Yeshak

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  2. Review
  3. Antimalarial Efficacy of Hydromethanolic Root Extract and Solvent Fractions ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  4. Review
  5. The GenusFrontiers in pharmacology · 2019
    Review
  6. Bioactive Constituents from the Aerial Parts ofMolecules (Basel, Switzerland) · 2018
    Article
  7. Antimalarial Activity of Plant Metabolites.International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Helen BitewDepartment of Pharmaceutical Chemistry and Pharmacognosy, School of pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa P.O. Box 9086, Ethiopia. helen.bitew@mu.edu.et.
Wendimagegn MammoDepartment of Chemistry, College of Natural and Computational Sciences, Addis Ababa University, Addis Ababa P.O. Box 1176, Ethiopia. wendimagegn.mammo@aau.edu.et.
Ariaya HymeteDepartment of Pharmaceutical Chemistry and Pharmacognosy, School of pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa P.O. Box 9086, Ethiopia. hymete@yahoo.com.
Mariamawit Yonathan YeshakDepartment of Pharmaceutical Chemistry and Pharmacognosy, School of pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa P.O. Box 9086, Ethiopia. mariamawit.yonathan@aau.edu.et.
Addis Ababa University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria is one of the world's most severe endemic diseases and due to the emergence of resistance to the currently available medicines, the need for new targets and relevant antimalarial drugs remains acute. The crude extract, four solvent fractions and two isolated compounds from the roots of

Indexed as

AnimalsAntimalarialsDisease Models, AnimalEchinops PlantFemaleMalariaMaleMiceParasitic Sensitivity TestsPlant ExtractsPlant RootsPlasmodium bergheiThiophenesAntimalarialsPlant ExtractsThiophenesacetylenicthiophenesacute oral toxicityEchinops hoehnelii Schweinfin vivo antimalarial

Identifiers

PMID29160791
PMCPMC6150322
OpenAlexW2770765860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.