ArticleMedical physics2018
The role of off-focus radiation in scatter correction for dedicated cone beam breast CT.
Article in Medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Artificial Intelligence in Breast X-Ray Imaging.Seminars in ultrasound, CT, and MR · 2023Review
- Cone-beam breast CT using an offset detector: effect of detector offset and image reconstruction algorithm.Physics in medicine and biology · 2022Article
- Radiation dosimetry of a clinical prototype dedicated cone-beam breast CT system with offset detector.Medical physics · 2021Article
- Characterization of x-ray focal spots using a rotating edge.Journal of medical imaging (Bellingham, Wash.) · 2021Article
- A residual dense network assisted sparse view reconstruction for breast computed tomography.Scientific reports · 2020Article
- Sparse-view, short-scan, dedicated cone-beam breast computed tomography: image quality assessment.Biomedical physics & engineering express · 2020Article
- Cone-beam breast computed tomography using ultra-fast image reconstruction with constrained, total-variation minimization for suppression of artifacts.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2020Article
- Dedicated cone-beam breast CT using laterally-shifted detector geometry: Quantitative analysis of feasibility for clinical translation.Journal of X-ray science and technology · 2020Article
- Shading correction for volumetric CT using deep convolutional neural network and adaptive filter.Quantitative imaging in medicine and surgery · 2019Article
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeDedicated cone beam breast CT (CBBCT) suffers from x-ray scatter contamination. We aim to identify the source of the significant difference between the scatter distributions estimated by two recent methods proposed by our group and to investigate its effect on CBBCT image quality.
methodWe recently proposed two novel methods of scatter correction for CBBCT, using a library based (LB) technique and a forward projection (FP) model. Despite similar enhancement on CBBCT image qualities, these two methods obtain very different scatter distributions. We hypothesize that the off-focus radiation (OFR) is the contributor and results in nontrivial signals in x-ray projections, which is ignored in the scatter estimation via the LB method. Experiments using a thin wire test tool are designed to study the effect of OFR on CBBCT spatial resolution by measuring the point spread function (PSF) and the modulation transfer function (MTF). A narrow collimator setting is used to suppress the OFR-induced signals. In addition, "PSFs" and "MTFs" are measured on clinical CBBCT images obtained by the LB and FP methods using small calcifications as point sources. The improvement of spatial resolution achieved by suppressing OFR in the wire experiment as well as in the clinical study is quantified by the improvement ratios of PSFs and spatial frequencies at different MTF values. Our hypothesis that OFR causes the imaging difference between the FP and LB methods is verified if these ratios obtained from experimental and clinical data are consistent.
resultsIn the wire experiment, the results show that suppression of OFR increases the maximum signal of the PSF by about 14% and reduces the full-width-at-half-maximum (FWHM) by about 12.0%. Similar improvement on spatial resolution is achieved by the FP method compared with the LB method in the patient study. The improvement ratios of spatial frequencies at different MTF values without OFR match very well in both studies at a level of around 16%, with an average root-mean-square difference of 0.47%.
conclusionThe results of the wire experiment and the clinical study indicate that the main difference between the LB and FP methods is whether the OFR-induced signals are included after scatter correction. Our study further shows that OFR significantly affects the image spatial resolution of CBBCT, indicating that the visualization of micro-calcifications is susceptible to OFR contamination. Our finding is therefore important in further improvement of diagnostic performance of CBBCT.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.