ArticleMolecular and cellular biochemistry2018
Diversity effect of capsaicin on different types of skeletal muscle.
Article in Molecular and cellular biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
- Quality of life, household income, and dietary habits are associated with the risk of sarcopenia among the Chinese elderly.Aging clinical and experimental research · 2024Article
- Dietary Capsaicin Reduces Chemically Induced Rat Urinary Bladder Carcinogenesis.Plant foods for human nutrition (Dordrecht, Netherlands) · 2023Article
- Article
- Succinate induces skeletal muscle fiber remodeling via SUNCR1 signaling.EMBO reports · 2019Article
- Article
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Authors and funding
16 authors at 1 institution in 1 country.
Funding
Abstract
Capsaicin is a major pungent content in green and red peppers which are widely used as spice, and capsaicin may activate different receptors. To determine whether capsaicin has different effects on different types of skeletal muscle, we applied different concentrations (0, 0.01, and 0.02%) of capsaicin in the normal diet and conducted a four-week experiment on Sprague-Dawley rats. The fiber type composition, glucose metabolism enzyme activity, and different signaling molecules' expressions of receptors were detected. Our results suggested that capsaicin reduced the body fat deposition, while promoting the slow muscle-related gene expression and increasing the enzyme activity in the gastrocnemius and soleus muscles. However, fatty acid metabolism was significantly increased only in the soleus muscle. The study of intracellular signaling suggested that the transient receptor potential vanilloid 1 (TRPV1) and cannabinoid receptors in the soleus muscle were more sensitive to capsaicin. In conclusion, the distribution of TRPV1 and cannabinoid receptors differs in different types of muscle, and the different roles of capsaicin in different types of muscle may be related to the different degrees of activation of receptors.
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Registered trials
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