Evidence map›Paper›PMID 29159603›Full record

Trial reportWorld journal of surgery2018

Prophylactic Intraperitoneal Onlay Mesh Reinforcement Reduces the Risk of Incisional Hernia, Two-Year Results of a Randomized Clinical Trial.

Philippe Brosi, Philippe M Glauser, Benjamin Speich, Samuel A Käser, Christoph A Maurer

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in World journal of surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01003067 (Intraperitoneal Mesh-Implementation After Laparotomy to Reduce Risk of Incisional Hernia), which is not on this map. Cited by 22 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01003067 naunknown statusnot on this map

Intraperitoneal Mesh-Implementation After Laparotomy to Reduce Risk of Incisional Hernia: a Prospective Randomized Controlled Trial

TypeinterventionalSponsorKantonsspital LiestalRan2008 to 2020Enrolled267ConditionsIncisional HerniaArmsMesh implementation
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  11. Optimal computed tomography-based biomarkers for prediction of incisional hernia formation.Hernia : the journal of hernias and abdominal wall surgery · 2024
    Article
  12. Review
  13. ONLAY VERSUS RIVES-STOPPA TECHNIQUES IN THE TREATMENT OF INCISIONAL HERNIAS.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philippe BrosiDepartment of Surgery, Hospital of Baselland, Affiliated to the University of Basel, Liestal, Switzerland.
Philippe M GlauserDepartment of Surgery, Hospital of Baselland, Affiliated to the University of Basel, Liestal, Switzerland.
Benjamin SpeichDepartment of Surgery, Hospital of Baselland, Affiliated to the University of Basel, Liestal, Switzerland.
Samuel A KäserDepartment of Surgery, Hospital of Baselland, Affiliated to the University of Basel, Liestal, Switzerland.
Christoph A MaurerDepartment of Surgery, Hospital of Baselland, Affiliated to the University of Basel, Liestal, Switzerland. christoph.maurer@hin.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncisional hernias still are a major concern after laparotomy and are causing substantial morbidity. This study examines the feasibility, safety and incisional hernia rate of the use of a prophylactic intraperitoneal onlay mesh stripe (IPOM) to prevent incisional hernia following midline laparotomy.

methodsThis prospective, randomized controlled trial randomly allocated patients undergoing median laparotomy either to mass closure of the abdominal wall with a PDS-loop running suture reinforced by an intraperitoneal composite mesh stripe (Group A) or to the same procedure without the additional mesh stripe (Group B). Primary endpoint was the incidence of incisional hernias at 2 years following midline laparotomy. Secondary endpoints are were the feasibility, the safety of the mesh stripe implantation including postoperative pain, and the incidence of incisional hernias at 5 years.

resultsA total of 267 patients were included in this study. Follow-up data 2 years after surgery was available from 210 patients (Group A = 107; Group B = 103). An incisional hernia was diagnosed in 18/107 (17%) patients in Group A and in 40/103 (39%) patients in Group B (p < 0.001). A surgical operation due to an incisional hernia was conducted for 12/107 (11%) patients in Group A and for 24/103 (23%) patients in Group B (p = 0.039). In both groups, minor and major complications as well as postoperative pain are reported with no statistically significant difference between the groups, even in contaminated situations.

conclusionsThis first randomized clinical trial indicates that the placement of a non-absorbable IPOM-stripe with prophylactic intention may significantly reduce the risk for a midline incisional hernia.

trial registrationRef. NCT01003067 (clinicaltrials.gov).

Indexed as

Abdominal Wound Closure TechniquesSurgical MeshAbdominal WallAgedFeasibility StudiesFemaleHernia, VentralHumansIncidenceIncisional HerniaLaparotomyMaleMiddle AgedProspective StudiesRisk FactorsSutures

Identifiers

PMID29159603

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.