ArticleClinical and experimental nephrology2018
Death with graft function after kidney transplantation: a single-center experience.
Article in Clinical and experimental nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- First-year all-cause kidney allograft loss: descriptive clinical trajectories of 92 events from a 17-year German transplant center cohort.BMC nephrology · 2026Article
- Renal transplantation in older recipients - results of the DZIF transplant cohort.BMC geriatrics · 2026Article
- The Detrimental Outcomes Associated With Kidney Delayed Graft Function Persist Beyond the Short Term.Transplantation direct · 2026Article
- Article
- Impact of Immunosenescence in Older Kidney Transplant Recipients: Associated Clinical Outcomes and Possible Risk Stratification for Immunosuppression Reduction.Drugs & aging · 2024Review
- Predictors of graft function and survival in second kidney transplantation: A single center experience.World journal of transplantation · 2023Article
- [Analysis of causes of graft loss in 135 kidney transplant recipients].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023Article
- Evaluation of Deceased Donor Kidney Transplantation in the Eurotransplant Senior Program in Comparison to Standard Allocation.Annals of transplantation · 2022Article
- Experiences of performing ABO-incompatible kidney transplantation in Bangladesh.Korean journal of transplantation · 2022Article
- Oral/oesophageal candidiasis is a risk factor for severe infection after kidney transplantation.Nephrology (Carlton, Vic.) · 2022Article
- Trends in the effects of pre-transplant diabetes on mortality and cardiovascular events after kidney transplantation.Journal of diabetes investigation · 2021Observational
- Subcutaneous phaeohyphomycosis caused by Hongkongmyces snookiorum in a kidney transplant patient: a case report.BMC infectious diseases · 2020Article
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Authors and funding
5 authors.
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Abstract
backgroundDeath with graft function (DWGF) is an important cause of long-term loss of grafts and patients. In this study, we investigated clinical characteristics and causes of DWGF in kidney transplant recipients.
methodsWe recruited kidney allograft recipients who underwent surgery during 1973-2016 at Seoul National University Hospital in Korea (n = 2137). We divided recipients into four groups: alive with graft function (AWGF), alive with graft loss (AWGL), DWGF, and death with graft loss (DWGL).
resultsAmong 455 recipients with graft loss, 88 (19.3%) lost graft function due to death. DWGF was responsible for 38.6% of a total of 228 deaths. Recipients with DWGF were older, more often diabetic, and experienced delayed graft function more often compared to patients with AWGF, AWGL, and DWGL. Additionally, they had fewer episodes of acute rejection than AWGF and AWGL patients. The majority of DWGF developed because of infection (40.9%), malignancy (28.4%), and cardiovascular disease (11.4%). Infection-related mortality was highest within the first year after transplantation. Death due to malignancy was lowest within the first year, but increased thereafter.
conclusionsIn our center, DWGF was a significant cause of graft loss. Infection and malignancy were the leading causes of DWGF during the overall post-transplantation period. Therefore, close monitoring for infection and malignancy should be instituted to lessen the burden of graft loss.
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