Evidence map›Paper›PMID 29159508›Full record

ArticleMolecular genetics and genomics : MGG2018

Comparative genomics and transcriptome analysis of Lactobacillus rhamnosus ATCC 11443 and the mutant strain SCT-10-10-60 with enhanced L-lactic acid production capacity.

Liang Sun, Zhilong Lu, Jianxiu Li, Feifei Sun, Ribo Huang

Abstract read
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In one paragraph

Article in Molecular genetics and genomics : MGG, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Liang SunCollege of Life Science and Technology, Guangxi University, Nanning, Guangxi, 530004, China.
Zhilong LuCollege of Life Science and Technology, Guangxi University, Nanning, Guangxi, 530004, China.
Jianxiu LiCollege of Life Science and Technology, Guangxi University, Nanning, Guangxi, 530004, China.
Feifei SunState Key Laboratory of Non-Food Biomass and Enzyme Technology, National Engineering Research Center for Non-Food Biorefinery, Guangxi Key Laboratory of Biorefinery, Guangxi Academy of Sciences, Nanning, Guangxi, 530007, China.
Ribo HuangCollege of Life Science and Technology, Guangxi University, Nanning, Guangxi, 530004, China. 1225342688@qq.com.ORCID http://orcid.org/0000-0002-1462-3095
Guangxi University · CNGuangxi Academy of Sciences · CN

Funding

Basic Science and Research Funding Program of Guangxi Academy of Science 12YJ25SW06National High Technology Research and Development Program ("863"Program) of China 2013AA050701
6 · The paper itself

Abstract

Mechanisms for high L-lactic acid production remain unclear in many bacteria. Lactobacillus rhamnosus SCT-10-10-60 was previously obtained from L. rhamnosus ATCC 11443 via mutagenesis and showed improved L-lactic acid production. In this study, the genomes of strains SCT-10-10-60 and ATCC 11443 were sequenced. Both genomes are a circular chromosome, 2.99 Mb in length with a GC content of approximately 46.8%. Eight split genes were identified in strain SCT-10-10-60, including two LytR family transcriptional regulators, two Rex redox-sensing transcriptional repressors, and four ABC transporters. In total, 60 significantly up-regulated genes (log

Indexed as

GenomicsGene Expression Regulation, BacterialGenome, BacterialLactic AcidLacticaseibacillus rhamnosusMetabolic EngineeringMutationPyruvic AcidTranscriptomeLactic AcidPyruvic AcidGenomeLactobacillus rhamnosusL-Lactic acidTranscriptome

Identifiers

PMID29159508
OpenAlexW2770971946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.