Evidence map›Paper›PMID 29159441›Full record

SynthesisJournal of abnormal child psychology2018

A Meta-Analysis of the Association Between Birth Weight and Attention Deficit Hyperactivity Disorder.

Allison M Momany, Jaclyn M Kamradt, Molly A Nikolas

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of abnormal child psychology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  6. The Evolving ADHD Phenotype in the Externalizing Context.The American journal of psychiatry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Allison M MomanyDepartment of Psychological and Brain Sciences, University of Iowa, E11 Seashore Hall, Iowa City, IA, 52242, USA. allison-momany@uiowa.edu.ORCID 0000-0002-5466-7973
Jaclyn M KamradtDepartment of Psychological and Brain Sciences, University of Iowa, E11 Seashore Hall, Iowa City, IA, 52242, USA.
Molly A NikolasDepartment of Psychological and Brain Sciences, University of Iowa, E11 Seashore Hall, Iowa City, IA, 52242, USA.

Funding

Mechanisms of Health and Disease at the Behavioral-Biomedical InterfaceT32GM108540 · NIGMS · UNIVERSITY OF IOWA · PI LUTGENDORF, SUSAN K, VOSS, MICHELLE WEBB · 2014 to 2023
$1.7M
NIGMS NIH HHS T32 GM108540
6 · The paper itself

Abstract

A large body of work has investigated the association between birth weight and ADHD and has resulted in mixed findings with regard to the direction and magnitude of this association. Despite the vast amount of research on this topic, a comprehensive and systematic quantification of the association between birth weight and ADHD has yet to be undertaken. A meta-analysis of 88 unique studies (N = 4,645,482) was conducted to quantify the overall effect size of birth weight on ADHD symptoms. Several variables were examined as moderators that may contribute to systematic variation in effect sizes. Overall, birth weight was found to have a small, but significant, association with ADHD symptoms such that individuals born at lower birth weights manifested greater symptoms of ADHD (r = -0.15). Sample type, mean birth weight of the sample, geographic region, the informant of ADHD symptoms, ADHD symptom measurement method, and race were all found to contribute significantly to heterogeneity in effect sizes. Notably, several early life risk factors previously found to be associated with both ADHD and birth weight, gestational age and prenatal smoking exposure, were not found to contribute to heterogeneity in effect sizes. The findings of the current analyses align with the growing recognition that early life adversity contributes to neurodevelopmental difficulties, and the findings highlight the importance of a better understanding of the mechanisms underlying the association between early life risk factors and adverse neurodevelopmental sequela, such as that observed in ADHD.

Indexed as

AdolescentAdultAttention Deficit Disorder with HyperactivityBirth WeightChildChild, PreschoolHumansInfant, Low Birth WeightYoung AdultAttention-deficit hyperactivity disorderBirth weightDevelopmental psychopathologyMeta-analysisPerinatal risk factors

Identifiers

PMID29159441
PMCPMC5962386

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.