ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2018
Analysis of macrolinguistic aspects of narratives from individuals with Alzheimer's disease, mild cognitive impairment, and no cognitive impairment.
Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 57 citations in OpenAlex.
- Advancing Alzheimer Disease Prediction With Large Language Model-Based Linguistic Feature Analysis: Development and Validation Study.JMIR medical informatics · 2026Article
- Linguistic Markers in Spontaneous Speech: Insights into Subjective Cognitive Decline (Review).Healthcare (Basel, Switzerland) · 2025Review
- Cognitive screening and education: assessing the Montreal Cognitive Assessment's validity in older Ugandan populations.Academia mental health & well-being · 2025Article
- Machine Learning Classification of Patients with Amnestic Mild Cognitive Impairment and Non-Amnestic Mild Cognitive Impairment from Written Picture Description Tasks.Brain sciences · 2024Article
- Language and communication rehabilitation in patients with schizophrenia: A narrative review.Heliyon · 2024Review
- Access to context-specific lexical-semantic information during discourse tasks differentiates speakers with latent aphasia, mild cognitive impairment, and cognitively healthy adults.Frontiers in human neuroscience · 2024Article
- Comparing global and local semantic coherence of spontaneous speech in persons with Alzheimer's disease and healthy controls.Applied Corpus Linguistics · 2023Article
- Can discourse processing performance serve as an early marker of Alzheimer's disease and mild cognitive impairment? A systematic review of text comprehension.European journal of ageing · 2022Review
- Speech- and Language-Based Classification of Alzheimer's Disease: A Systematic Review.Bioengineering (Basel, Switzerland) · 2022Review
- Characteristics Scanning of Brain Structure and Function Changes in Patients with Different Degrees of Alzheimer's Disease.Contrast media & molecular imaging · 2022Article
- Lower Education and Reading and Writing Habits Are Associated With Poorer Oral Discourse Production in Typical Adults and Older Adults.Frontiers in psychology · 2022Article
- Article
- Using Digital Speech Assessments to Detect Early Signs of Cognitive Impairment.Frontiers in digital health · 2021Article
- Using a Discourse Task to Explore Semantic Ability in Persons With Cognitive Impairment.Frontiers in aging neuroscience · 2020Article
- Narrative impairment, white matter damage and CSF biomarkers in the Alzheimer's disease spectrum.Aging · 2019Article
- Speech Analysis by Natural Language Processing Techniques: A Possible Tool for Very Early Detection of Cognitive Decline?Frontiers in aging neuroscience · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe depiction of features in discourse production promotes accurate diagnosis and helps to establish the therapeutic intervention in cognitive impairment and dementia. We aimed to identify alterations in the macrolinguistic aspects of discourse using a new computational tool.
methodsSixty individuals, aged 60 years and older, were distributed in three different groups: mild Alzheimer's disease (mAD), amnestic mild cognitive impairment, and healthy controls. A narrative created by individuals was analyzed through the Coh-Metrix-Dementia program, extracting the features of interest automatically.
resultsmAD showed worse overall performance compared to the other groups: less informative discourse, greater impairment in global coherence, greater modalization, and inferior narrative structure. It was not possible to discriminate between amnestic mild cognitive impairment and healthy controls. DISCUSSION: Our results are in line with the literature, verifying a pathological change in the macrostructure of discourse in mAD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.