Evidence map›Paper›PMID 29159185›Full record

ArticleBioMed research international2017

Design and Testing of an Experimental Steam-Induced Burn Model in Rats.

Vlad Porumb, Alexandru Florentin Trandabăț, Cristina Terinte, Irina Draga Căruntu, Elena Porumb-Andrese, Mihail Gabriel Dimofte, Dragoş Pieptu

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Evaluation of wound healing potential of pomegranate (Journal of advanced veterinary and animal research · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Vlad PorumbDepartment of Surgery, School of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 University Street, 700115 Iaşi, Romania.ORCID 0000-0002-0891-4857
Alexandru Florentin TrandabățDepartment of Electrical Measurements and Materials, School of Electrical Engineering, Gheorghe Asachi Technical University, 3 Dimitrie Mangeron Street, 700050 Iaşi, Romania.ORCID 0000-0001-7280-7653
Cristina TerinteDepartment of Pathology, Regional Institute of Oncology, 2-4 General Henri Mathias Berthelot Street, 700483 Iaşi, Romania.ORCID 0000-0003-0434-9069
Irina Draga CăruntuDepartment of Morpho-Functional Sciences I-Histology, School of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 University Street, 700115 Iaşi, Romania.ORCID 0000-0002-0104-8503
Elena Porumb-AndreseDepartment of Dermatology, School of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 University Street, 700115 Iaşi, Romania.ORCID 0000-0002-2859-2066
Mihail Gabriel DimofteDepartment of Surgery, School of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 16 University Street, 700115 Iaşi, Romania.
Dragoş PieptuSecond Surgery Clinic, Regional Institute of Oncology, 2-4 General Henri Mathias Berthelot Street, 700483 Iaşi, Romania.
Grigore T. Popa University of Medicine and Pharmacy · ROGheorghe Asachi Technical University of Iași · ROInstitutul Regional de Oncologie · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMost of the current models for experimental burns pose difficulties in ensuring consistency and standardization. AIM OF STUDY: We aimed to develop an automated, reproducible technique for experimental burns using steam-based heat transfer.

methodsThe system developed for steam exposure was based on a novel, integrated, computer-controlled design. Three groups of rats were exposed to steam for 1, 3, and 7 seconds. The lesions were evaluated after 20 minutes, 48 hours, and 72 hours after burn induction.

resultsOne-second steam application produced a superficial second-degree burn; three-second application induced deep second-degree burn; and seven-second application led to a third-degree burn.

conclusionThe high level of automation of our integrated, computer-controlled system makes the difference between our system and other models, by ensuring the control of the duration of exposure, temperature, and pressure and eliminating as many potential human generated errors as possible. The automated system can accurately reproduce specific types of burns, according to histological assessment. This model could generate the reproducible data needed in the study of burn pathology and in order to assess new treatments.

Indexed as

BurnsWound HealingAnimalsDisease Models, AnimalHot TemperatureHumansRatsRats, WistarSteamSteam

Identifiers

PMID29159185
PMCPMC5660770
OpenAlexW2762369157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.