Evidence map›Paper›PMID 29159108›Full record

ArticleJournal of clinical & translational endocrinology2015

Insulin resistance in Saudi postmenopausal women with and without metabolic syndrome and its association with vitamin D deficiency.

Eman M Alissa, Wafa A Alnahdi, Nabil Alama, Gordon A Ferns

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical & translational endocrinology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Association of Hypovitaminosis D with Metabolic Syndrome in Postmenopausal Women.Journal of obstetrics and gynaecology of India · 2020
    Review
  6. Vitamin D Status and Cardio-Metabolic Risk in Indian Postmenopausal Women.Journal of clinical and diagnostic research : JCDR · 2016
    Article
  7. Vitamin D deficiency in Thailand.Journal of clinical & translational endocrinology · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Eman M AlissaFaculty of Medicine, King Abdulaziz University, P.O. Box 12713, Jeddah 21483, Saudi Arabia.
Wafa A AlnahdiFaculty of Medicine, King Abdulaziz University, P.O. Box 12713, Jeddah 21483, Saudi Arabia.
Nabil AlamaFaculty of Medicine, King Abdulaziz University, P.O. Box 12713, Jeddah 21483, Saudi Arabia.
Gordon A FernsMedical Education and Metabolic Medicine, Brighton and Sussex Medical School, University of Brighton, BN1 9PH, UK.
King Abdulaziz University · SABrighton and Sussex Medical School · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is increasing interest in the non-skeletal effects of vitamin D and the relationship between vitamin D deficiency and chronic conditions such as diabetes mellitus. We aimed to investigate the relationship between surrogate indices of insulin resistance (IR), and vitamin D deficiency/insufficiency in postmenopausal Saudi women with and without metabolic syndrome.

methodsThe study population consisted of 300 postmenopausal women aged 46-88 years enrolled consecutively from women attending the Outpatient Clinics of King Abdulaziz University Hospital. Demographic, anthropometric, and biochemical parameters were recorded. Data were analyzed for women with and without metabolic syndrome.

resultsAbdominal obesity, IR, and hypovitaminosis D were highly prevalent within our population sample. Of the components used to define metabolic syndrome; waist circumference, serum triglycerides (TG), high density lipoprotein-cholesterol, and fasting blood glucose (FBG) were significantly related with all surrogate measures of IR. Significant inverse correlations were found between serum vitamin D and serum TG, FBG, and diastolic blood pressure, within the study cohort.

conclusionsThese observations suggest that hypovitaminosis D may be associated with the risk of developing metabolic syndrome. Interrelationships between IR, metabolic syndrome, and hypovitaminosis D are of particular interest in Saudi population, given the high prevalence of these conditions in this region.

Indexed as

25(OH)D3, 25-Hydroxyvitamin D3AHA/NHLBI, American Heart Association/National Heart Lung and Blood InstituteBMI, body mass indexDBP, diastolic blood pressureFBG, fasting blood glucoseHDL-C, high density lipoprotein-cholesterolHOMA-IR, homeostasis model assessment for insulin resistanceInsulin resistanceIR, Insulin resistanceKAUH, King Abdulaziz University HospitalLDL-C, low-density lipoprotein-cholesterolMetabolic syndromePostmenopausal womenPTH, parathyroid hormoneQUICKI, quantitative insulin sensitivity check index-ISaudiSBP, systolic blood pressureSD, standard deviationTG, triglyceridesVitamin D

Identifiers

PMID29159108
PMCPMC5685048
OpenAlexW2048192646

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.