Evidence map›Paper›PMID 29159020›Full record

ReviewActa pharmaceutica Sinica. B2017

The current agonists and positive allosteric modulators of

Taoyi Yang, Ting Xiao, Qi Sun, Kewei Wang

Open access · diamondAbstract readReview
In one paragraph

Review in Acta pharmaceutica Sinica. B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 116 citations in OpenAlex.

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  11. Hidden complexity of α7 nicotinic acetylcholine receptor desensitization revealed by MD simulations and Markov state modeling.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Taoyi YangDepartment of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Ting XiaoDepartment of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Qi SunState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Kewei WangDepartment of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Peking University · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The alpha-7 nicotinic acetylcholine receptor (

Indexed as

5-CSRTT, five-choice serial reaction time task5-HT, serotoninAcetylcholineACh, acetylcholineAD, Alzheimer's diseaseADHD, attention deficit hyperactivity disorderAlpha7Alzheimer's diseaseAβ, amyloid-β peptideCNS, central nervous systemDMTS, delayed matching-to-sampleECD, extracellular domainGABA, γ-aminobutyric acidIon channelMLA, methyllycaconitinenAChRnAChR, nicotinic acetylcholine receptorNOR, novel object recognitionPAMs, positive allosteric modulatorsPCP, neonatal phencyclidinePD, Parkinson's diseasePositive allosteric modulatorsPPI, prepulse inhibitionSAR, structure–activity relationshipSchizophreniaTMD, transmembrane domainsα-Btx, α-bungarotoxin

Identifiers

PMID29159020
PMCPMC5687317
OpenAlexW2767064823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.